4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]Benzaldehyde

Base Information

Chemical Name:4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]Benzaldehyde
CAS No.:167264-41-7
Molecular Formula:C15H24 O2 Si
Molecular Weight:264.44
Hs Code.:
DSSTox Substance ID:DTXSID00699094
Wikidata:Q82629821

Synonyms:167264-41-7;Benzaldehyde,4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-;4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]Benzaldehyde;4-(2-t-butyldimethylsiloxyethyl)benzaldehyde;4-[2-[tert-butyl(dimethyl)silyl]oxyethyl]benzaldehyde;SCHEMBL2356225;DTXSID00699094;JMVFNZRCHHTZMU-UHFFFAOYSA-N;FT-0767185;4-(2-((tert-Butyldimethylsilyl)oxy)ethyl)benzaldehyde;4-(2-{[tert-Butyl(dimethyl)silyl]oxy}ethyl)benzaldehyde;4-(2-{[tert-butyl(dimethyl)silyl]-oxy}ethyl)benzaldehyde

Suppliers and Price of 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]Benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]Benzaldehyde

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:264.154556538
Heavy Atom Count:18
Complexity:260

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)[Si](C)(C)OCCC1=CC=C(C=C1)C=O

Technology Process of 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]Benzaldehyde

There total 5 articles about 4-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]Benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 73899-15-7
1-(t-butyldimethylsilyloxy)-2-(4-bromophenyl)ethane

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 167264-41-7
4-[2-(t-butyldimethylsilyloxy)ethyl]benzaldehyde

Guidance literature:: 1-(t-butyldimethylsilyloxy)-2-(4-bromophenyl)ethane; With n-butyllithium; In tetrahydrofuran; hexane; at -90 - -80 ℃; for 1h; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -100 - -10 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/chem.201101978

Reference yield:

: 4654-39-1
4-bromophenethanol

: 167264-41-7
4-[2-(t-butyldimethylsilyloxy)ethyl]benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1H-imidazole / dichloromethane / 1 h / 20 °C / Inert atmosphere; Cooling with water bath

2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -90 - -80 °C / Inert atmosphere

2.2: 0.5 h / -100 - -10 °C / Inert atmosphere

With 1H-imidazole; n-butyllithium; In tetrahydrofuran; hexane; dichloromethane; 2.2: Wittig reaction;
DOI:10.1002/chem.201101978

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 167264-41-7
4-[2-(t-butyldimethylsilyloxy)ethyl]benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1H-imidazole / dichloromethane / 1 h / 20 °C / Inert atmosphere; Cooling with water bath

2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -90 - -80 °C / Inert atmosphere

2.2: 0.5 h / -100 - -10 °C / Inert atmosphere

With 1H-imidazole; n-butyllithium; In tetrahydrofuran; hexane; dichloromethane; 2.2: Wittig reaction;
DOI:10.1002/chem.201101978