tert-butyl-(3S,αS)-3-(N-benzyl-N-(α-methylbenzyl)amino)-6-hydroxyhexanoate

Base Information

Chemical Name:tert-butyl-(3S,αS)-3-(N-benzyl-N-(α-methylbenzyl)amino)-6-hydroxyhexanoate
CAS No.:852052-54-1
Molecular Formula:C₂₅H₃₅NO₃
Molecular Weight:397.558
Hs Code.:

Synonyms:tert-butyl-(3S,αS)-3-(N-benzyl-N-(α-methylbenzyl)amino)-6-hydroxyhexanoate

Suppliers and Price of tert-butyl-(3S,αS)-3-(N-benzyl-N-(α-methylbenzyl)amino)-6-hydroxyhexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of tert-butyl-(3S,αS)-3-(N-benzyl-N-(α-methylbenzyl)amino)-6-hydroxyhexanoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of tert-butyl-(3S,αS)-3-(N-benzyl-N-(α-methylbenzyl)amino)-6-hydroxyhexanoate

There total 1 articles about tert-butyl-(3S,αS)-3-(N-benzyl-N-(α-methylbenzyl)amino)-6-hydroxyhexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 17480-69-2
(S)-N-benzyl-1-phenylethylamine

: 852052-53-0
tert-butyl-(E)-6-hydroxyhex-2-enoate

: 852052-54-1
tert-butyl-(3S,αS)-3-(N-benzyl-N-(α-methylbenzyl)amino)-6-hydroxyhexanoate

Guidance literature:: (S)-N-benzyl-1-phenylethylamine; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h;

tert-butyl-(E)-6-hydroxyhex-2-enoate; In tetrahydrofuran; at -78 ℃; for 2h;
DOI:10.1039/b500223k

Reference yield: 87.0%

: 852052-54-1
tert-butyl-(3S,αS)-3-(N-benzyl-N-(α-methylbenzyl)amino)-6-hydroxyhexanoate

: 852052-45-0
tert-butyl (3S,αS)-3-(N-benzyl-(α-methylbenzyl)amino)-6-oxohexanoate

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 - 20 ℃; for 1.33333h;
DOI:10.1039/b500223k

Reference yield:

: 852052-54-1
tert-butyl-(3S,αS)-3-(N-benzyl-N-(α-methylbenzyl)amino)-6-hydroxyhexanoate

: 104553-43-7
(2S,αS)-tert-butyl pyrrolidin-2-yl-acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / oxalyl chloride; DMSO; Et₃N / CH₂Cl₂ / 1.33 h / -78 - 20 °C

2: 96 percent / H₂ / Pd(OH)2/C / methanol / 16 h / 3800 Torr

With oxalyl dichloride; hydrogen; dimethyl sulfoxide; triethylamine; palladium dihydroxide; In methanol; dichloromethane; 1: Swern oxidation;
DOI:10.1039/b500223k