N-benzyl N-methyl O-benzoylbenzamide

Base Information

• Chemical Name: N-benzyl N-methyl O-benzoylbenzamide
• CAS No.: 79984-96-6
• Molecular Formula: C₂₂H₁₉NO₂
• Molecular Weight: 329.398
• Mol file: 79984-96-6.mol

Synonyms:N-benzyl N-methyl O-benzoylbenzamide

Chemical Property of N-benzyl N-methyl O-benzoylbenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of N-benzyl N-methyl O-benzoylbenzamide

There total 2 articles about N-benzyl N-methyl O-benzoylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Benzoylbenzoic acid (85-52-9) + benzyl-methyl-amine (103-67-3) → N-benzyl N-methyl O-benzoylbenzamide (79984-96-6)

Guidance literature:

2-Benzoylbenzoic acid; benzyl-methyl-amine; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 0.0833333h;

With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 15h;

DOI:10.1039/c4ob01948b

Reference yield:

3-chloro-3-phenylphthalide (18852-53-4) + benzyl-methyl-amine (103-67-3) → N-benzyl N-methyl O-benzoylbenzamide (79984-96-6)

Guidance literature:

In chloroform; at 0 ℃; for 1h;

Reference yield: 37.0%

N-benzyl N-methyl O-benzoylbenzamide (79984-96-6) → 4-hydroxy-2-methyl-3,4-diphenyl-3,4-dihydroisoquinolin-1(2H)-one + 2-methyl-3,4-diphenylisoquinolin-1(2H)-one

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; at 90 ℃; for 3h; Inert atmosphere;

DOI:10.1039/c4ob01948b

upstream raw materials:

3-chloro-3-phenylphthalide

benzyl-methyl-amine

2-Benzoylbenzoic acid

Downstream raw materials:

3-phenylphthalide

1,1'-diphenyl-1H,1'H-[1,1']biisobenzofuranyl-3,3'-dione