(E)-N-methyl-N-[4-(4-benzylpiperazinyl)sulfonylphenyl]-3-(4-methylsulfonylphenyl)-2-propenamide

Base Information

Chemical Name:(E)-N-methyl-N-[4-(4-benzylpiperazinyl)sulfonylphenyl]-3-(4-methylsulfonylphenyl)-2-propenamide
CAS No.:134907-81-6
Molecular Formula:C₂₈H₃₁N₃O₅S₂
Molecular Weight:553.703
Hs Code.:

Synonyms:(E)-N-methyl-N-[4-(4-benzylpiperazinyl)sulfonylphenyl]-3-(4-methylsulfonylphenyl)-2-propenamide

Suppliers and Price of (E)-N-methyl-N-[4-(4-benzylpiperazinyl)sulfonylphenyl]-3-(4-methylsulfonylphenyl)-2-propenamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-N-methyl-N-[4-(4-benzylpiperazinyl)sulfonylphenyl]-3-(4-methylsulfonylphenyl)-2-propenamide

Chemical Property:

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Technology Process of (E)-N-methyl-N-[4-(4-benzylpiperazinyl)sulfonylphenyl]-3-(4-methylsulfonylphenyl)-2-propenamide

There total 10 articles about (E)-N-methyl-N-[4-(4-benzylpiperazinyl)sulfonylphenyl]-3-(4-methylsulfonylphenyl)-2-propenamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 134907-72-5
(E)‐3‐(4‐(methylsulfonyl)phenyl)acryloyl chloride

: 134907-58-7
1-benzyl-4-<<4-(methylamino)phenyl>sulfonyl>piperazine

: 134907-81-6
(E)-N-methyl-N-[4-(4-benzylpiperazinyl)sulfonylphenyl]-3-(4-methylsulfonylphenyl)-2-propenamide

Guidance literature:: With pyridine; In dichloromethane; for 2h; Ambient temperature;
DOI:10.1021/jm00111a048

Reference yield:

: 2759-28-6
1-phenylmethylpiperazine

: 134907-81-6
(E)-N-methyl-N-[4-(4-benzylpiperazinyl)sulfonylphenyl]-3-(4-methylsulfonylphenyl)-2-propenamide

Guidance literature:: Multi-step reaction with 3 steps

1: CH₃COONa / ethanol / 4 h / Ambient temperature

2: 1 N aq. NaOH / ethanol / Heating

3: pyridine / CH₂Cl₂ / 2 h / Ambient temperature

With pyridine; sodium hydroxide; sodium acetate; In ethanol; dichloromethane;
DOI:10.1021/jm00111a048

Reference yield:

: 39169-92-1
4-(N-acetyl-N-methylamino)benzenesulfonyl chloride

: 134907-81-6
(E)-N-methyl-N-[4-(4-benzylpiperazinyl)sulfonylphenyl]-3-(4-methylsulfonylphenyl)-2-propenamide

Guidance literature:: Multi-step reaction with 3 steps

1: CH₃COONa / ethanol / 4 h / Ambient temperature

2: 1 N aq. NaOH / ethanol / Heating

3: pyridine / CH₂Cl₂ / 2 h / Ambient temperature

With pyridine; sodium hydroxide; sodium acetate; In ethanol; dichloromethane;
DOI:10.1021/jm00111a048