(2R,3R,4S,5R,6S)-2-(benzoyloxymethyl)-6-(3-benzyloxy-3',4',5'-trimethoxybiphenyl-4-yloxy)tetrahydro-2H-pyran-3,4,5-triyl tribenzoate

Base Information

• Chemical Name: (2R,3R,4S,5R,6S)-2-(benzoyloxymethyl)-6-(3-benzyloxy-3',4',5'-trimethoxybiphenyl-4-yloxy)tetrahydro-2H-pyran-3,4,5-triyl tribenzoate
• CAS No.: 1204502-33-9
• Molecular Formula: C₅₆H₄₈O₁₄
• Molecular Weight: 944.989
• Mol file: 1204502-33-9.mol

Synonyms:(2R,3R,4S,5R,6S)-2-(benzoyloxymethyl)-6-(3-benzyloxy-3',4',5'-trimethoxybiphenyl-4-yloxy)tetrahydro-2H-pyran-3,4,5-triyl tribenzoate

Chemical Property of (2R,3R,4S,5R,6S)-2-(benzoyloxymethyl)-6-(3-benzyloxy-3',4',5'-trimethoxybiphenyl-4-yloxy)tetrahydro-2H-pyran-3,4,5-triyl tribenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (2R,3R,4S,5R,6S)-2-(benzoyloxymethyl)-6-(3-benzyloxy-3',4',5'-trimethoxybiphenyl-4-yloxy)tetrahydro-2H-pyran-3,4,5-triyl tribenzoate

There total 1 articles about (2R,3R,4S,5R,6S)-2-(benzoyloxymethyl)-6-(3-benzyloxy-3',4',5'-trimethoxybiphenyl-4-yloxy)tetrahydro-2H-pyran-3,4,5-triyl tribenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

3-benzyloxy-3',4',5'-trimethoxybiphenyl-4-ol (1204502-32-8) + O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl) trichloroacetimidate (149707-76-6) → (2R,3R,4S,5R,6S)-2-(benzoyloxymethyl)-6-(3-benzyloxy-3',4',5'-trimethoxybiphenyl-4-yloxy)tetrahydro-2H-pyran-3,4,5-triyl tribenzoate (1204502-33-9)

Guidance literature:

3-benzyloxy-3',4',5'-trimethoxybiphenyl-4-ol; O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl) trichloroacetimidate; In dichloromethane; at -10 ℃; for 0.5h; Molecular sieve;

With boron trifluoride diethyl etherate; In dichloromethane; at -10 ℃;

DOI:10.1039/b916969e

Reference yield: 83.0%

(2R,3R,4S,5R,6S)-2-(benzoyloxymethyl)-6-(3-benzyloxy-3',4',5'-trimethoxybiphenyl-4-yloxy)tetrahydro-2H-pyran-3,4,5-triyl tribenzoate (1204502-33-9) → (2R,3R,4S,5R,6S)-2-(benzoyloxymethyl)-6-(3,4'-dihydroxy-3',5'-dimethoxybiphenyl-4-yloxy)tetrahydro-2H-pyran-3,4,5-triyl tribenzoate (1204502-34-0)

Guidance literature:

With magnesium iodide; at 80 ℃; for 5h; neat (no solvent);

DOI:10.1039/b916969e

upstream raw materials:

3-benzyloxy-3',4',5'-trimethoxybiphenyl-4-ol

O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl) trichloroacetimidate

Downstream raw materials:

(2R,3R,4S,5R,6S)-2-(benzoyloxymethyl)-6-(3,4'-dihydroxy-3',5'-dimethoxybiphenyl-4-yloxy)tetrahydro-2H-pyran-3,4,5-triyl tribenzoate