Desmethyletizolam

Base Information

Chemical Name:Desmethyletizolam
CAS No.:40054-68-0
Molecular Formula:C₁₆H₁₃ClN₄S
Molecular Weight:328.825
Hs Code.:
UNII:K1C6XI9LLX
ChEMBL ID:CHEMBL4782672
DSSTox Substance ID:DTXSID101032847
Wikidata:Q21098977
Wikipedia:Metizolam

Synonyms:4-(2-chlorophenyl)-2-ethyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine;metizolam

Suppliers and Price of Desmethyletizolam

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 28 raw suppliers

Chemical Property of Desmethyletizolam

Chemical Property:

Melting Point:153-154 °C
Boiling Point:527.2±60.0 °C(Predicted)
Density:1.46±0.1 g/cm3(Predicted)
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:328.0549453
Heavy Atom Count:22
Complexity:446

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC1=CC2=C(S1)N3C=NN=C3CN=C2C4=CC=CC=C4Cl

Technology Process of Desmethyletizolam

There total 3 articles about Desmethyletizolam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 33671-37-3
5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]1,4-diazepin-2-one

: 40054-68-0
4-(2-chlorophenyl)-2-ethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine

Guidance literature:: Multi-step reaction with 3 steps

1: P₂S₅, Py / 1 h / 80 °C

2: N₂H₄*H₂O / methanol / Ambient temperature

3: H₂SO₄ / ethanol / 5 h / Heating

With pyridine; tetraphosphorus decasulfide; sulfuric acid; hydrazine hydrate; In methanol; ethanol;

Reference yield:

: 40054-40-8
5-(2-chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-thione

: 40054-68-0
4-(2-chlorophenyl)-2-ethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine

Guidance literature:: Multi-step reaction with 2 steps

1: N₂H₄*H₂O / methanol / Ambient temperature

2: H₂SO₄ / ethanol / 5 h / Heating

With sulfuric acid; hydrazine hydrate; In methanol; ethanol;