diethyl 4-(phenylethynyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Base Information

• Chemical Name: diethyl 4-(phenylethynyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• CAS No.: 114984-32-6
• Molecular Formula: C₂₁H₂₃NO₄
• Molecular Weight: 353.418
• Mol file: 114984-32-6.mol

Synonyms:diethyl 4-(phenylethynyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property of diethyl 4-(phenylethynyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of diethyl 4-(phenylethynyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

There total 2 articles about diethyl 4-(phenylethynyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Phenylpropargyl aldehyde (2579-22-8) + ethyl aminocrotonate (626-34-6,7318-00-5,41867-20-3) → diethyl 4-(phenylethynyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (114984-32-6)

Guidance literature:

With acetic acid; In ethanol; at 100 ℃; for 0.0166667h; Solvent; Microwave irradiation; Sealed tube;

DOI:10.3762/bjoc.9.232

Reference yield: 96.0%

Phenylpropargyl aldehyde (2579-22-8) + ethyl acetoacetate (141-97-9) → diethyl 4-(phenylethynyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (114984-32-6)

Guidance literature:

With ammonium acetate; acetic acid; In ethanol; at 120 ℃; for 0.0833333h; Microwave irradiation; Sealed tube;

DOI:10.3762/bjoc.9.232

upstream raw materials:

Phenylpropargyl aldehyde

ethyl aminocrotonate

ethyl acetoacetate