N-benzyl-3-hydroxy-N,N-dimethylpropanammonium bromide

Base Information

• Chemical Name: N-benzyl-3-hydroxy-N,N-dimethylpropanammonium bromide
• CAS No.: 133001-69-1
• Molecular Formula: Br*C₁₂H₂₀NO
• Molecular Weight: 274.201
• Mol file: 133001-69-1.mol

Synonyms:N-benzyl-3-hydroxy-N,N-dimethylpropanammonium bromide

Chemical Property of N-benzyl-3-hydroxy-N,N-dimethylpropanammonium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzyl-3-hydroxy-N,N-dimethylpropanammonium bromide

There total 1 articles about N-benzyl-3-hydroxy-N,N-dimethylpropanammonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3-Dimethylamino-1-propanol (3179-63-3) + benzyl bromide (100-39-0) → N-benzyl-3-hydroxy-N,N-dimethylpropanammonium bromide (133001-69-1)

Guidance literature:

In acetonitrile; for 4h; Reflux;

DOI:10.1016/j.ejmech.2013.05.033

Reference yield: 70.0%

hexadecyl dihydrogen phosphate (3539-43-3) + N-benzyl-3-hydroxy-N,N-dimethylpropanammonium bromide (133001-69-1) → 2-[benzyl(dimethyl)ammonio]propyl hexadecyl phosphate (1448798-76-2)

Guidance literature:

hexadecyl dihydrogen phosphate; With pyridine; at 50 ℃; for 2h;

N-benzyl-3-hydroxy-N,N-dimethylpropanammonium bromide; With 2,4,6-triisopropylphenylsulfonyl chloride; In pyridine; at 40 ℃;

DOI:10.1016/j.ejmech.2013.05.033

Reference yield: 24.0%

2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethyl dihydrogen phosphate + N-benzyl-3-hydroxy-N,N-dimethylpropanammonium bromide (133001-69-1) → 3-[benzyl(dimethyl)ammonio]propyl 2-[(2,2,4,4-tetramethylpentane-2-yl)oxy]ethyl phosphate (1448798-79-5)

Guidance literature:

2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethyl dihydrogen phosphate; With pyridine; at 50 ℃; for 2h;

N-benzyl-3-hydroxy-N,N-dimethylpropanammonium bromide; With 2,4,6-triisopropylphenylsulfonyl chloride; In pyridine; at 40 ℃;

DOI:10.1016/j.ejmech.2013.05.033

upstream raw materials:

3-Dimethylamino-1-propanol

benzyl bromide

Downstream raw materials:

o-Xylyl-<3-hydroxy-hexyl>-methylamin

2-[benzyl(dimethyl)ammonio]propyl hexadecyl phosphate

3-[benzyl(dimethyl)ammonio]propyl 2-[(2,2,4,4-tetramethylpentane-2-yl)oxy]ethyl phosphate