C₂₅H₃₆O₆

Base Information

• Chemical Name: C₂₅H₃₆O₆
• CAS No.: 1384271-68-4
• Molecular Formula: C₂₅H₃₆O₆
• Molecular Weight: 432.557
• Mol file: 1384271-68-4.mol

Synonyms:C₂₅H₃₆O₆

Chemical Property of C₂₅H₃₆O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₃₆O₆

There total 14 articles about C₂₅H₃₆O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(3S)-3-[(4-methoxybenzyl)oxy]-4-pentenoic acid (935475-92-6) + (R)-1-((4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)pentan-2-ol (1384271-69-5) → C25H36O6 (1384271-68-4)

Guidance literature:

(3S)-3-[(4-methoxybenzyl)oxy]-4-pentenoic acid; With 2,4,6-trichlorobenzoyl chloride; triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

(R)-1-((4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)pentan-2-ol; With dmap; In toluene; at 0 - 20 ℃; for 12h;

DOI:10.1016/j.tetlet.2012.04.118

Reference yield:

(S)-1-(1,3-dithian-2-yl)but-3-en-2-ol (959129-32-9) → C25H36O6 (1384271-68-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetra-(n-butyl)ammonium iodide; sodium hydride / tetrahydrofuran / 0 - 20 °C

2.1: calcium carbonate; methyl iodide / water; acetonitrile / 3 h / 45 °C

3.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; acetonitrile / 6 h / 20 °C

4.1: 2,4,6-trichlorobenzoyl chloride; triethylamine / tetrahydrofuran / 4 h / 0 - 20 °C

4.2: 12 h / 0 - 20 °C

With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; 2,4,6-trichlorobenzoyl chloride; tetra-(n-butyl)ammonium iodide; sodium hydride; triethylamine; calcium carbonate; methyl iodide; In tetrahydrofuran; water; acetonitrile; 4.1: Yamaguchi reaction / 4.2: Yamaguchi reaction;

DOI:10.1016/j.tetlet.2012.04.118

Reference yield:

C29H40O3Si (1384271-75-3) → C25H36O6 (1384271-68-4)

Guidance literature:

Multi-step reaction with 9 steps

1.1: methanol; toluene-4-sulfonic acid / 0 - 20 °C

2.1: sodium tetrahydroborate; nickel diacetate / ethanol; ethylene glycol / 6 h / 20 °C

3.1: titanium(IV) isopropylate; tert.-butylhydroperoxide; L-(+)-diisopropyl tartrate / dichloromethane / 12 h / -20 °C / Molecular sieve

4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 °C

4.2: -78 °C

5.1: sodium hexamethyldisilazane / tetrahydrofuran / 0 - 20 °C

6.1: scandium tris(trifluoromethanesulfonate) / tetrahydrofuran; water / 12 h / 20 °C

7.1: camphor-10-sulfonic acid / dichloromethane / 0 - 20 °C

8.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C

9.1: 2,4,6-trichlorobenzoyl chloride; triethylamine / tetrahydrofuran / 4 h / 0 - 20 °C

9.2: 12 h / 0 - 20 °C

With titanium(IV) isopropylate; methanol; tert.-butylhydroperoxide; sodium tetrahydroborate; oxalyl dichloride; L-(+)-diisopropyl tartrate; 2,4,6-trichlorobenzoyl chloride; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; sodium hexamethyldisilazane; nickel diacetate; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; scandium tris(trifluoromethanesulfonate); In tetrahydrofuran; ethanol; dichloromethane; water; ethylene glycol; 3.1: Sharpless epoxidation / 4.1: Swern oxidation / 4.2: Swern oxidation / 9.1: Yamaguchi reaction / 9.2: Yamaguchi reaction;

DOI:10.1016/j.tetlet.2012.04.118

upstream raw materials:

(3S)-3-[(4-methoxybenzyl)oxy]-4-pentenoic acid

(R)-1-((4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)pentan-2-ol

(S)-1-(1,3-dithian-2-yl)but-3-en-2-ol

C₁₆H₂₂O₂S₂

Downstream raw materials:

C₂₃H₃₂O₆

C₂₃H₃₂O₆