935475-92-6Relevant academic research and scientific papers
Total synthesis of nonenolide
Meshram, Harshadas Mitaram,Kumar, Dachepally Aravind,Ramesh, Palakuri
, p. 1422 - 1427 (2010)
A novel synthetic route has been reported for the synthesis of nonenolide. The syntheses of fragments were initiated from commercially available and inexpensive starting materials. The synthesis involves key steps like Sharpless epoxidation, Jacobsen's re
A stereoselective total synthesis of decarestrictine I
Yadav, Jhillu Singh,Venkatesh, Miriyal,Kumar, Alleni Suman,Reddy, Poli Adi Narayana,Reddy, Basi V. Subba,Prasad, Attaluri R.
, p. 830 - 838 (2014/07/07)
A convergent and stereoselective total synthesis of decarestrictine I, a polyketide natural product, is described. Both acid and alcohol fragments were prepared from the readily available L-malic acid via Still-Gennari olefination and Sharpless asymmetric epoxidation. The Steglich esterification and ring-closing metathesis (RCM) are employed to combine both acid and alcohol fragments. Copyright
First stereoselective total synthesis of Phomolide G and H via RCM protocol
Ramesh, Palakuri,Chennakesava Reddy,Meshram
scheme or table, p. 3735 - 3738 (2012/09/22)
A first total synthetic route has been reported for the synthesis of Phomolide G and H. The syntheses of fragments were initiated from commercially available and inexpensive starting material (R)-epichlorohydrin. The synthesis involves a key Sharpless epo
Total synthesis of Z-isomer of phomolide B
Mohapatra, Debendra K.,Reddy, D. Prabhakar,Dash, Uttam,Yadav
scheme or table, p. 151 - 154 (2011/02/26)
We have achieved the synthesis of Z-isomer of phomolide B during our investigation toward the effect of protecting group on the outcome of ring-closing metathesis reaction. The other key reactions involved are cis-selective partial hydrogenation, Sharples
First stereoselective total synthesis of decarestrictine O via RCM protocol
Krishna, Palakodety Radha,Rao, T. Jagannadha
scheme or table, p. 4017 - 4019 (2010/08/07)
A convergent first stereoselective total synthesis of decarestrictine O via RCM protocol starting from 1,3-propanediol and propylene oxide is reported.
Total synthesis of decarestrictine i and botryolide B via RCM protocol
Radha Krishna, Palakodety,Rao, T. Jagannadha
supporting information; experimental part, p. 3130 - 3132 (2010/08/21)
A convergent stereoselective total synthesis of decarestrictine I (1) and botryolide B (1a) invoking a common synthetic strategy is reported. The key steps are: ring-closing metathesis of epoxy dienoic esters obtained through the Yamaguchi esterification
Total synthesis of achaetolide from D-mannitol
Rao, K. Sripad,Chattapadhyay, Amit Kumar,Ghosh, Subhash
scheme or table, p. 3078 - 3080 (2011/02/25)
A highly convergent stereoselective total synthesis of achaetolide, a ten-membered lactone is described. The ring-closing metathesis reaction was used to construct the macrocycle and E-olefinic moiety in the molecule. The key acid and alcohol fragments we
Total syntheses and absolute stereochemistry of decarestrictines C1 and C2
Mohapatra, Debendra K.,Sahoo, Gokarneswar,Ramesh, Dhondi K.,Rao, J. Srinivasa,Sastry, G. Narahari
scheme or table, p. 5636 - 5639 (2011/02/22)
The total syntheses of decarestrictines C1 and C2 have been described. The synthetic strategy involves a practical and flexible approach using esterification and ring-closing metathesis to unite the acid and alcohol fragments. The ac
Protecting group directed ring-closing metathesis (RCM): the first total synthesis of an anti-malarial nonenolide
Mohapatra, Debendra K.,Ramesh, Dhondi K.,Giardello, Michael A.,Chorghade, Mukund S.,Gurjar, Mukund K.,Grubbs, Robert H.
, p. 2621 - 2625 (2007/10/03)
The first synthesis of a newly found naturally occurring anti-malarial nonenolide is described. A pivotal step in the synthesis is the ring-closing metathesis of a dienoic ester prepared by coupling an acid and alcohol that were stereoselectively synthesi
