Technology Process of 2-((1-(4-(tert-butyl)phenyl)vinyl)oxy)isoindoline-1,3-dione
There total 5 articles about 2-((1-(4-(tert-butyl)phenyl)vinyl)oxy)isoindoline-1,3-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridine; oxygen; copper diacetate; sodium sulfate;
In
1,2-dichloro-ethane;
at 20 ℃;
for 48h;
DOI:10.1021/ja506579t
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tert.-butyl lithium / diethyl ether; hexane / 0.5 h / -78 °C
1.2: -78 °C
2.1: hydrogenchloride / water / 2 h / 20 °C
3.1: copper diacetate; sodium sulfate; pyridine; oxygen / 1,2-dichloro-ethane / 48 h / 20 °C
With
pyridine; hydrogenchloride; tert.-butyl lithium; oxygen; copper diacetate; sodium sulfate;
In
diethyl ether; hexane; water; 1,2-dichloro-ethane;
DOI:10.1021/ja506579t
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: acetic acid; lithium bromide; sodium periodate / 20 °C
2.1: potassium carbonate / methanol; tetrahydrofuran / 3 h / 20 °C
3.1: tert.-butyl lithium / diethyl ether; hexane / 0.5 h / -78 °C
3.2: -78 °C
4.1: hydrogenchloride / water / 2 h / 20 °C
5.1: copper diacetate; sodium sulfate; pyridine; oxygen / 1,2-dichloro-ethane / 48 h / 20 °C
With
pyridine; hydrogenchloride; sodium periodate; tert.-butyl lithium; oxygen; copper diacetate; potassium carbonate; acetic acid; sodium sulfate; lithium bromide;
In
tetrahydrofuran; methanol; diethyl ether; hexane; water; 1,2-dichloro-ethane;
DOI:10.1021/ja506579t
