C₂₁H₂₄N₂O₂

Base Information

• Chemical Name: C₂₁H₂₄N₂O₂
• CAS No.: 1379589-66-8
• Molecular Formula: C₂₁H₂₄N₂O₂
• Molecular Weight: 336.434
• Mol file: 1379589-66-8.mol

Synonyms:C₂₁H₂₄N₂O₂

Chemical Property of C₂₁H₂₄N₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₂₄N₂O₂

There total 3 articles about C₂₁H₂₄N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(pyridin-3-yl)ethanamine hydrochloride (84359-16-0) + 1,1'-carbonyldiimidazole (530-62-1) + (2E, 4E)-7-phenylhepta-2,4-dien-1-ol → C21H24N2O2 (1379589-66-8)

Guidance literature:

1,1'-carbonyldiimidazole; (2E, 4E)-7-phenylhepta-2,4-dien-1-ol; In dichloromethane; at 20 ℃; for 3h;

2-(pyridin-3-yl)ethanamine hydrochloride; With triethylamine; In dichloromethane; at 20 ℃; for 72h;

Reference yield:

ethyl (2E)-5-phenylpent-2-enoate (55282-95-6) → C21H24N2O2 (1379589-66-8)

Guidance literature:

Multi-step reaction with 4 steps

1.1: diisobutylaluminium hydride / toluene; hexane / 6 h / -78 °C

1.2: 20 °C / pH 1

1.3: 15 h / 20 °C

2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C

2.2: 1 h / -78 °C

3.1: diisobutylaluminium hydride / toluene; hexane / 3 h / -78 °C

3.2: 20 °C / pH 1 / Cooling with ice

4.1: dichloromethane / 3 h / 20 °C

4.2: 72 h / 20 °C

With sodium hydride; diisobutylaluminium hydride; In tetrahydrofuran; hexane; dichloromethane; toluene; mineral oil;

Reference yield:

(2E,4E)-ethyl 7-phenylhepta-2,4-dienoate (477531-94-5) → C21H24N2O2 (1379589-66-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: diisobutylaluminium hydride / toluene; hexane / 3 h / -78 °C

1.2: 20 °C / pH 1 / Cooling with ice

2.1: dichloromethane / 3 h / 20 °C

2.2: 72 h / 20 °C

With diisobutylaluminium hydride; In hexane; dichloromethane; toluene;

upstream raw materials:

2-(pyridin-3-yl)ethanamine hydrochloride

1,1'-carbonyldiimidazole

ethyl (2E)-5-phenylpent-2-enoate

(2E,4E)-ethyl 7-phenylhepta-2,4-dienoate