2-(((2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-pyridine-4-carbonyl)-amino)-thiazol-4-yl)-acetic acid ethyl ester

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Chemical Name:2-(((2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-pyridine-4-carbonyl)-amino)-thiazol-4-yl)-acetic acid ethyl ester
CAS No.:1168142-59-3
Molecular Formula:C₂₃H₂₅N₃O₇S₂
Molecular Weight:519.599
Hs Code.:

Synonyms:2-(((2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-pyridine-4-carbonyl)-amino)-thiazol-4-yl)-acetic acid ethyl ester

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Chemical Property of 2-(((2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-pyridine-4-carbonyl)-amino)-thiazol-4-yl)-acetic acid ethyl ester

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Technology Process of 2-(((2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-pyridine-4-carbonyl)-amino)-thiazol-4-yl)-acetic acid ethyl ester

There total 1 articles about 2-(((2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-pyridine-4-carbonyl)-amino)-thiazol-4-yl)-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.75%

: 53266-94-7
ethyl 2-amino-1,3-thiazol-4-acetate

: 1168143-82-5
2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-isonicotinic acid

: 1168142-59-3
2-(((2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-pyridine-4-carbonyl)-amino)-thiazol-4-yl)-acetic acid ethyl ester

Guidance literature:: 2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-isonicotinic acid; With benzotriazol-1-ol; diisopropyl-carbodiimide; In N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

ethyl 2-amino-1,3-thiazol-4-acetate; In N,N-dimethyl-formamide; at 100 ℃; for 1h;

Reference yield: 63.48%

: 1168142-59-3
2-(((2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-pyridine-4-carbonyl)-amino)-thiazol-4-yl)-acetic acid ethyl ester

: 1168142-60-6
2-(((2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-pyridine-4-carbonyl)-amino)-thiazol-4-yl)-acetic acid

Guidance literature:: 2-(((2-isopropoxy-6-(4-methanesulfonyl-phenoxy)-pyridine-4-carbonyl)-amino)-thiazol-4-yl)-acetic acid ethyl ester; With water; sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; water; pH=2; Acidic aqueous solution;