Technology Process of m-(carbomethoxy)valerophenone
There total 5 articles about m-(carbomethoxy)valerophenone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3-methylpyridin-2-ylamine; chlorobis(ethylene)rhodium(I) dimer; ethyl crotonate; 1,3-bis(2,4,6-trimethylphenyl)4,5-dimethyl-1,3-dihydro-2H-imidazol-2-ylidene; water; toluene-4-sulfonic acid;
In
2-methyltetrahydrofuran;
at 150 ℃;
for 120h;
Inert atmosphere;
Glovebox;
Sealed tube;
DOI:10.1021/jacs.8b02462
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 32 g / diethyl ether; benzene / 2 h / Heating
2: 22 g / sodium dichromate, conc. sulfuric acid / benzene; H2O; acetic acid / 3 h / Ambient temperature
3: 11 g / 30percent KOH / ethanol / Heating
4: 18 g / sodium bicarbonate / dimethylformamide / Ambient temperature
With
potassium hydroxide; sodium dichromate; sulfuric acid; sodium hydrogencarbonate;
In
diethyl ether; ethanol; water; acetic acid; N,N-dimethyl-formamide; benzene;
DOI:10.1021/ja00414a048
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 11 g / 30percent KOH / ethanol / Heating
2: 18 g / sodium bicarbonate / dimethylformamide / Ambient temperature
With
potassium hydroxide; sodium hydrogencarbonate;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1021/ja00414a048
