2-Deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-5-methanesulfonyl-D-arabinitol

Base Information

Chemical Name:2-Deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-5-methanesulfonyl-D-arabinitol
CAS No.:302593-25-5
Molecular Formula:C₂₈H₃₁NO₆S
Molecular Weight:509.623
Hs Code.:

Synonyms:2-Deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-5-methanesulfonyl-D-arabinitol

Suppliers and Price of 2-Deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-5-methanesulfonyl-D-arabinitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-5-methanesulfonyl-D-arabinitol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-5-methanesulfonyl-D-arabinitol

There total 8 articles about 2-Deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-5-methanesulfonyl-D-arabinitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 302593-20-0
methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

: 302593-25-5
2-Deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-5-methanesulfonyl-D-arabinitol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 0.166667h;
DOI:10.1055/s-2000-6408

Reference yield:

: Methyl 2-azido-2-deoxy-3,4:5,6-O-diisopropylidene-L-idonate

: 302593-25-5
2-Deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-5-methanesulfonyl-D-arabinitol

Guidance literature:: Multi-step reaction with 7 steps

1: H₂ / 10 percent Pd/C / ethyl acetate / 5 h / 20 °C

2: 6.14 g / Pb(NO₃)2; Et₃N / CH₂Cl₂ / 48 h / 20 °C

3: 95 percent / Dowex 50W-X₈ / methanol / 20 h / 20 °C

4: aq. NaIO₄ / ethanol / 1 h / 20 °C

5: 0.80 g / NaBH₄ / aq. ethanol / 0.5 h / 0 °C

6: 96 percent / Et₃N / tetrahydrofuran / 0.25 h / 0 °C

7: 97 percent / LiAlH₄ / tetrahydrofuran / 0.17 h / 0 °C

With sodium tetrahydroborate; sodium periodate; lithium aluminium tetrahydride; lead(II) nitrate; Dowex 50W-X₈; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane; ethyl acetate; 1: Reduction / 2: Substitution / 3: Ring cleavage / 4: Oxidation / 5: Reduction / 6: Substitution / 7: Reduction;
DOI:10.1055/s-2000-6408

Reference yield:

: 55135-66-5
9-bromo-9-phenyl-9H-fluorene

: 302593-25-5
2-Deoxy-2-[(9-phenylfluoren-9-yl)amino]-3,4-O-isopropylidene-5-methanesulfonyl-D-arabinitol

Guidance literature:: Multi-step reaction with 6 steps

1: 6.14 g / Pb(NO₃)2; Et₃N / CH₂Cl₂ / 48 h / 20 °C

2: 95 percent / Dowex 50W-X₈ / methanol / 20 h / 20 °C

3: aq. NaIO₄ / ethanol / 1 h / 20 °C

4: 0.80 g / NaBH₄ / aq. ethanol / 0.5 h / 0 °C

5: 96 percent / Et₃N / tetrahydrofuran / 0.25 h / 0 °C

6: 97 percent / LiAlH₄ / tetrahydrofuran / 0.17 h / 0 °C

With sodium tetrahydroborate; sodium periodate; lithium aluminium tetrahydride; lead(II) nitrate; Dowex 50W-X₈; triethylamine; In tetrahydrofuran; methanol; ethanol; dichloromethane; 1: Substitution / 2: Ring cleavage / 3: Oxidation / 4: Reduction / 5: Substitution / 6: Reduction;
DOI:10.1055/s-2000-6408