N-(4-aminomethyl-2-ethynyl-6-fluoro-phenyl)-methanesulfonamide hydrochloride

Base Information

Chemical Name:N-(4-aminomethyl-2-ethynyl-6-fluoro-phenyl)-methanesulfonamide hydrochloride
CAS No.:953090-75-0
Molecular Formula:C₁₀H₁₁FN₂O₂S*ClH
Molecular Weight:278.735
Hs Code.:

Synonyms:N-(4-aminomethyl-2-ethynyl-6-fluoro-phenyl)-methanesulfonamide hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-aminomethyl-2-ethynyl-6-fluoro-phenyl)-methanesulfonamide hydrochloride

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Technology Process of N-(4-aminomethyl-2-ethynyl-6-fluoro-phenyl)-methanesulfonamide hydrochloride

There total 1 articles about N-(4-aminomethyl-2-ethynyl-6-fluoro-phenyl)-methanesulfonamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 911124-11-3
tert-butyl 3-ethynyl-5-fluoro-4-(methylsulfonamido)benzylcarbamate

: 953090-75-0
N-(4-aminomethyl-2-ethynyl-6-fluoro-phenyl)-methanesulfonamide hydrochloride

Guidance literature:: With hydrogenchloride; In water; ethyl acetate; Reflux;
DOI:10.1016/j.bmc.2009.10.043

Reference yield: 100.0%

: 953090-75-0
N-(4-aminomethyl-2-ethynyl-6-fluoro-phenyl)-methanesulfonamide hydrochloride

: 3-(2-morpholin-4-yl-6-trifluoromethyl-pyridin-3-yl)-acrylic acid

: (E)-N-(3-ethynyl-5-fluoro-4-methanesulfonylamino-benzyl)-3-(2-morpholin-4-yl-6-trifluoromethyl-pyridin-3-yl)-acrylamide

Guidance literature:

Reference yield: 95.0%

: 54022-99-0
5-(3-trifluoromethylphenyl)furan-2-carboxylic acid

: 953090-75-0
N-(4-aminomethyl-2-ethynyl-6-fluoro-phenyl)-methanesulfonamide hydrochloride

: 1202642-80-5
5-(3-trifluoromethyl-phenyl)-furan-2-carboxylic acid 3-ethynyl-5-fluoro-4-methanesulfonylamino-benzylamide

Guidance literature:: With 4-methyl-morpholine; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In tetrahydrofuran; at 20 ℃;