2',3-Dimethyl-4-aminobiphenyl

Base Information

• Chemical Name: 2',3-Dimethyl-4-aminobiphenyl
• CAS No.: 13394-86-0
• Molecular Formula: C₁₄H₁₅N
• Molecular Weight: 197.28
• Hs Code.: 2921499090
• DSSTox Substance ID: DTXSID50158429
• Nikkaji Number: J3.438J
• Wikidata: Q26841228
• ChEMBL ID: CHEMBL310395
• Mol file: 13394-86-0.mol

Synonyms:2',3-dimethyl-4-aminobiphenyl;2',3-dimethyl-4-aminobiphenyl hydrochloride;3,2'-dimethyl-4-aminobiphenyl

Chemical Property of 2',3-Dimethyl-4-aminobiphenyl

Chemical Property:

• Refractive Index: 1.4870 (estimate)
• Boiling Point: 310.4°Cat760mmHg
• PKA: 4.18±0.10(Predicted)
• Flash Point: 146.5°C
• PSA: 26.02000
• Density: 1.04g/cm³
• LogP: 4.13380
• Storage Temp.: Refrigerator
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 197.120449483
• Heavy Atom Count: 15
• Complexity: 202

Purity/Quality:

98%Min ^*data from raw suppliers

4-Amino-3,2''-dimethylbiphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 3
• Hazard Codes: 3

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1C2=CC(=C(C=C2)N)C
• Uses: Potential carcinogen found in dairy products.

Technology Process of 2',3-Dimethyl-4-aminobiphenyl

There total 5 articles about 2',3-Dimethyl-4-aminobiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

2-Methylphenylboronic acid (16419-60-6) + 4-Bromo-2-methylaniline (583-75-5) → 2',3 dimethyl 4 aminobiphenyl (13394-86-0)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; water; at 80 ℃; Inert atmosphere;

Reference yield:

2,3'-Dimethyl-4'-nitro-biphenyl (40915-19-3) → 2',3 dimethyl 4 aminobiphenyl (13394-86-0)

Guidance literature:

With methanol; nickel; Hydrogenation;

Reference yield:

(3,2'-dimethyl-biphenyl-4-yl)-o-tolyl-diazene (857484-43-6) → 2',3 dimethyl 4 aminobiphenyl (13394-86-0)

Guidance literature:

With hydrogenchloride; tin(ll) chloride;

upstream raw materials:

2,3'-Dimethyl-4'-nitro-biphenyl

(3,2'-dimethyl-biphenyl-4-yl)-o-tolyl-diazene

4-nitro-3-methylaniline

2-Methylphenylboronic acid

Downstream raw materials:

bis-(3,2'-dimethyl-biphenyl-4-yl)-diazene

N,N'-bis-(3,2'-dimethyl-biphenyl-4-yl)-hydrazine

3,2'-Dimethyl-4-nitroso-biphenyl

N-(3,2'-Dimethyl-biphenyl-4-yl)-hydroxylamine