Acetoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester

Base Information

• Chemical Name: Acetoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester
• CAS No.: 92516-25-1
• Molecular Formula: C₁₄H₁₈O₅
• Molecular Weight: 266.294
• Mol file: 92516-25-1.mol

Synonyms:Acetoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester

Chemical Property of Acetoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester

There total 4 articles about Acetoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

acetic anhydride (108-24-7) + Ethoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester (92516-20-6) → Acetoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester (92516-25-1)

Guidance literature:

In pyridine;

DOI:10.1246/bcsj.57.1510

Reference yield:

Cyanhydrin von 2.6-Dimethyl-4-methoxybenzaldehyd (70242-29-4) → Acetoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester (92516-25-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 76 percent / HCl(g) / ethanol / 3 h / 50 °C

2: 1.) 30percent aq KOH

3: 92 percent / TsOH / Heating

4: 95 percent / pyridine

With hydrogenchloride; potassium hydroxide; toluene-4-sulfonic acid; In pyridine; ethanol;

DOI:10.1246/bcsj.57.1510

Reference yield:

4-methoxy-2,6-dimethylbenzylaldehyde (19447-00-8) → Acetoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester (92516-25-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 77 percent / CaO / 2 h / 50 °C

2: 76 percent / HCl(g) / ethanol / 3 h / 50 °C

3: 1.) 30percent aq KOH

4: 92 percent / TsOH / Heating

5: 95 percent / pyridine

With hydrogenchloride; potassium hydroxide; calcium oxide; toluene-4-sulfonic acid; In pyridine; ethanol;

DOI:10.1246/bcsj.57.1510

upstream raw materials:

acetic anhydride

Ethoxy-(4-methoxy-2,6-dimethyl-phenyl)-acetic acid methyl ester

4-methoxy-2,6-dimethylbenzylaldehyde

Cyanhydrin von 2.6-Dimethyl-4-methoxybenzaldehyd

Downstream raw materials:

(2-(2,4-dinitrophenyl)hydrazono)acetic acid

2,4-dinitrophenylhydrazone of methyl glyoxylate

1,3-dibromo-6-methoxy-2,4-dimethylbenzene