19447-00-8

Usage

Uses

Used in Fragrance Industry:
4-METHOXY-2,6-DIMETHYLBENZALDEHYDE is used as a fragrance ingredient for its strong sweet, floral odor, adding depth and complexity to perfumes and personal care products.
Used in Organic Synthesis:
4-METHOXY-2,6-DIMETHYLBENZALDEHYDE is used as a versatile building block in organic synthesis, enabling the creation of a wide range of chemical compounds.
Used in Household and Industrial Product Production:
4-METHOXY-2,6-DIMETHYLBENZALDEHYDE is used as a key ingredient in the production of various household and industrial products, including fragrances, deodorants, and air fresheners, due to its pleasant odor and reactivity.
Used in Pharmaceutical and Agrochemical Synthesis:
4-METHOXY-2,6-DIMETHYLBENZALDEHYDE is utilized in the synthesis of pharmaceuticals and agrochemicals, leveraging its unique properties and reactivity for the development of new and effective products in these industries.

Upstream product

• 74-90-8 hydrogen cyanide 
• 874-63-5 3,5-dimethylmethoxybenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 70547-87-4 2,6-dimethyl-4-hydroxybenzaldehyde 
• 77-78-1 dimethyl sulfate 
• 2591-86-8 N-Formylpiperidine 
• 90609-47-5 1-iodo-2,6-dimethyl-4-methoxybenzene 
• 4885-02-3 Dichloromethyl methyl ether 
• 557-21-1 dicyanozinc 
• 108-68-9 3,5-Dimethylphenol 
• 6267-34-1 2-bromo-5-methoxy-1,3-dimethyl-benzene 
• 1634-04-4 tert-butyl methyl ether 
• 594-19-4 tert.-butyl lithium 
• 74-88-4 methyl iodide 

Downstream Products

• 103796-15-2 3,5-dimethyl-4-(trans-2-nitro-vinyl)-anisole 
• 21573-41-1 3,4,5-Trimethylanisole 
• 61019-03-2 5-methoxy-1,3-dimethyl-2-nitrobenzene 
• 37934-89-7 2,6-Dimethyl-4-methoxybenzoic acid 
• 38718-66-0 5-methoxy-benzene-1,2,3-tricarboxylic acid trimethyl ester 
• 90-02-8 salicylaldehyde 
• 111086-51-2 (1S,2R)-1,2-Bis-(4-methoxy-2,6-dimethyl-phenyl)-ethane-1,2-diamine 
• 111086-64-7 C₃₄H₃₆N₂O₄ 
• 111086-72-7 C₃₄H₃₆N₂O₄ 
• 113379-16-1 (E)-3-(4-Methoxy-2,6-dimethyl-phenyl)-acrylic acid ethyl ester 
• 111159-87-6 2-<(4-metoxy-2,6-dimethylphenyl)methylene>hydrazinecarboximidamide 
• 103409-08-1 N⁴-[1-(4-Methoxy-2,6-dimethyl-phenyl)-meth-(E)-ylidene]-[1,2,4]triazole-3,4-diamine 
• 61000-21-3 (4-methoxy-2,6-dimethylphenyl)methanol 
• 88791-55-3 2,6-Dimethyl-4-methoxy-benzaldoxim 

Relevant academic research and scientific papers

Direct synthesis of G-2N

The synthesis of angularly fused quinone natural products has been achieved using a photoenolization reaction and a Diels-Alder reaction in the key carbon-carbon bond forming steps.

A Pyrolytic Approach to 2-Hydroxy-7-methoxy-5-methyl-1-naphthoic Acid

Condensation of 4-methoxy-2,6-dimethylbenzaldehyde with Meldrum's acid, and flash vacuum pyrolysis of the condensation product (12) gave in almost quantitative yield 7-methoxy-5-methyl-2-naphthol (9).This naphthol is a precursor of the title 1-carboxylic acid (6), an intercalating moiety of enediyne and other antibiotics.

Formylation of electron-rich aromatic rings mediated by dichloromethyl methyl ether and TiCl4: Scope and limitations

Here the aromatic formylation mediated by TiCl4 and dichloromethyl methyl ether previously described by our group has been explored for a wide range of aromatic rings, including phenols, methoxy- and methylbenzenes, as an excellent way to produce aromatic aldehydes. Here we determine that the regioselectivity of this process is highly promoted by the coordination between the atoms present in the aromatic moiety and those in the metal core.

A direct and mild formylation method for substituted benzenes utilizing dichloromethyl methyl ether-silver trifluoromethanesulfonate

A silver trifluoromethanesulfonate (AgOTf)-promoted direct and mild formylation of benzenes has been developed. The reaction utilizing dichloromethyl methyl ether (Cl2CHOMe) and AgOTf powerfully formylated various substituted benzenes under temperature conditions as low as -78 C without losing the protecting groups on the phenolic hydroxyl group.

Acid-labile cys-protecting groups for the Fmoc/tBu strategy: Filling the gap

To address the existing gap in the current set of acid-labile Cys-protecting groups for the Fmoc/tBu strategy, diverse Fmoc-Cys(PG)-OH derivatives were prepared and incorporated into a model tripeptide to study their stability against TFA. S-Dpm proved to be compatible with the commonly used S-Trt group and was applied for the regioselecive construction of disulfide bonds.

Acid-labile cys-protecting groups for the Fmoc/tBu strategy: Filling the gap

To address the existing gap in the current set of acid-labile Cys-protecting groups for the Fmoc/tBu strategy, diverse Fmoc-Cys(PG)-OH derivatives were prepared and incorporated into a model tripeptide to study their stability against TFA. S-Dpm proved to be compatible with the commonly used S-Trt group and was applied for the regioselecive construction of disulfide bonds.

Synthesis of novel structurally simplified estrogen analogues with electron-donating groups in ring A

A library of 25 novel estrogen analogues were prepared in five to eight steps from mostly commercially available substituted anisoles via bromination, formylation, Corey-Fuchs reaction, elimination, and Sonogashira reaction. Georg Thieme Verlag Stuttgart.

THYROID HORMONE ANALOGUES AND METHODS FOR THEIR PREPARATION

Thyroid hormone analogues are disclosed. Methods of using such analogues and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.

De novo design, synthesis, and evaluation of novel nonsteroidal phenanthrene ligands for the estrogen receptor

Although there are many estrogen receptor antagonists with improved tissue selectivity profiles compared with tamoxifen, optimal tissue selectivity has not yet been demonstrated. As such there is still a need for additional diversity and new chemical scaf

An enantiospecific approach to 8,9-seco-C-aromatic taxanes

An enantiospecific approach to functionalised C-aromatic-8,9-seco-taxanes starting from the readily available monoterpene (R)-carvone is described.