Guanidinoethyl disulfide

Base Information

• Chemical Name: Guanidinoethyl disulfide
• CAS No.: 1072-13-5
• Molecular Formula: C₆H₁₆N₆S₂
• Molecular Weight: 236.365
• Hs Code.: 2930909090
• UNII: ON58WN42P2
• DSSTox Substance ID: DTXSID40910255
• Nikkaji Number: J78.491E
• ChEMBL ID: CHEMBL105278
• Mol file: 1072-13-5.mol

Synonyms:bis(2-guanidinoethyl)disulfide;bis(2-guanidinoethyl)disulfide dihydrobromide;guanidinoethyldisulfide

Chemical Property of Guanidinoethyl disulfide

Chemical Property:

• Vapor Pressure: 4.47E-09mmHg at 25°C
• Refractive Index: 1.5500 (estimate)
• Boiling Point: 471.9°Cat760mmHg
• Flash Point: 239.2°C
• PSA: 174.40000
• Density: 1.52g/cm³
• LogP: 1.71580
• Storage Temp.: 2-8°C
• XLogP3: -2.2
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 236.08778688
• Heavy Atom Count: 14
• Complexity: 175

Purity/Quality:

98%,99%, ^*data from raw suppliers

GUANIDINOETHYL DISULFIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CSSCCN=C(N)N)N=C(N)N
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Technology Process of Guanidinoethyl disulfide

There total 5 articles about Guanidinoethyl disulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

S-(2-aminoethyl)isothiouronium bromide hydrobromide (56-10-0) → guanidinoethyldisulfide (1072-13-5)

Guidance literature:

With sodium hydroxide; air;

DOI:10.1248/cpb.14.1193

Reference yield:

N-(2-mercaptoethyl)guanidine (1190-74-5) → guanidinoethyldisulfide (1072-13-5)

Guidance literature:

With Amberlite IRA 402 (OH-) resin; In water;

DOI:10.1111/j.1476-5381.1996.tb15589.x

Reference yield:

2-Guanidinoethanethiosulphonic acid (7176-65-0) → guanidinoethyldisulfide (1072-13-5)

Guidance literature:

With hydrogen sulfide;

DOI:10.1021/jo00823a005

upstream raw materials:

S-(2-aminoethyl)isothiouronium bromide hydrobromide

2-Guanidinoethanethiosulphonic acid

N-(2-mercaptoethyl)guanidine

CYANAMID

Refernces

• 1、 Foye,Hebb,Mickles. "Antiradiation compounds. 8. Reaction of thiols with cyanogen bromide.". . p. 292 - 293. Retrieved 1967.