2-TETRAHYDROFURYL HYDROPEROXIDE

Base Information

• Chemical Name: 2-TETRAHYDROFURYL HYDROPEROXIDE
• CAS No.: 4676-82-8
• Molecular Formula: C₄H₈O₃
• Molecular Weight: 104.106
• Mol file: 4676-82-8.mol

Synonyms:Tetrahydrofuran-2-hydroperoxid;2-hydroperoxytetrahydrofuran;2-tetrahydrofuryl hydroperoxide;tetrahydrofuran-2-yl-hydroperoxide;2-hydroperoxotetrahydrofyran;Tetrahydrofuran-2-hydroperoxide;

Chemical Property of 2-TETRAHYDROFURYL HYDROPEROXIDE

Chemical Property:

• Refractive Index: 1.4462 (estimate)
• Boiling Point: 135.22°C (rough estimate)
• PSA: 38.69000
• Density: 1.1141 (rough estimate)
• LogP: 0.61250

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): 3
• Hazard Codes: 3

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-TETRAHYDROFURYL HYDROPEROXIDE

There total 3 articles about 2-TETRAHYDROFURYL HYDROPEROXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(Z)-2,3,4,6-tetraphenylhex-3-en-5-yn-2-ol (864943-35-1) + tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) → 2-hydroperoxytetrahydrofuran (4676-82-8) + 5-methyl-3,4,5-triphenyl-5H-furan-2-one (29021-87-2) + benzoic acid (65-85-0,8013-63-6)

Guidance literature:

With oxygen; silver trifluoromethanesulfonate; (triphenylphosphine)gold(I) chloride; at 50 ℃; for 17h;

DOI:10.1021/ja062610q

Reference yield: 82.0%

(Z)-2-(2-chlorophenyl)-3,4-diphenyldec-3-en-5-yn-2-ol (864943-41-9) + tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) → 2-hydroperoxytetrahydrofuran (4676-82-8) + 5-(2-chlorophenyl)-5-methyl-3,4-diphenyl-5H-furan-2-one + valeric acid (109-52-4)

Guidance literature:

With oxygen; silver trifluoromethanesulfonate; (triphenylphosphine)gold(I) chloride; at 50 ℃; for 3h;

DOI:10.1021/ja062610q

Reference yield:

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) → 2-hydroperoxytetrahydrofuran (4676-82-8) + 4-butanolide (96-48-0)

Guidance literature:

With Fe₂(HPTP)Cl₄ClO₄; dihydrogen peroxide; In acetonitrile;

DOI:10.1515/znb-1999-1009

upstream raw materials:

tetrahydrofuran

(Z)-2,3,4,6-tetraphenylhex-3-en-5-yn-2-ol

(Z)-2-(2-chlorophenyl)-3,4-diphenyldec-3-en-5-yn-2-ol

Downstream raw materials:

4-butanolide

4-hydroxybutyraldehyde

2-hydroxytetrahydrofuran

3-(tetrahydrofuran-2-yl)propanenitrile

Refernces

• 1、 Bhakat, Manotosh,Biswas, Promita,Dey, Jayanta,Guin, Joyram. "Heteroarylation of Ethers, Amides, and Alcohols with Light and O2". supporting information. p. 6886 - 6890. Retrieved 2021/09/14.