1-(2-benzyloxyphenyl)-4-phenylbutadiene

Base Information

• Chemical Name: 1-(2-benzyloxyphenyl)-4-phenylbutadiene
• CAS No.: 206755-80-8
• Molecular Formula: C₂₃H₂₂O
• Molecular Weight: 314.427
• Mol file: 206755-80-8.mol

Synonyms:1-(2-benzyloxyphenyl)-4-phenylbutadiene

Chemical Property of 1-(2-benzyloxyphenyl)-4-phenylbutadiene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 1-(2-benzyloxyphenyl)-4-phenylbutadiene

There total 1 articles about 1-(2-benzyloxyphenyl)-4-phenylbutadiene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-phenyl-propionaldehyde (104-53-0) + 2-benzyloxybenzyltriphenylphosphonium chloride → 1-(2-benzyloxyphenyl)-4-phenylbutadiene (206755-80-8)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; for 3h; Heating;

DOI:10.1248/cpb.46.639

Reference yield: 92.0%

1-(2-benzyloxyphenyl)-4-phenylbutadiene (206755-80-8) → 2-(4-phenylbutyl)phenol (167145-50-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 60 ℃; for 5h;

DOI:10.1248/cpb.46.639

Reference yield:

1-(2-benzyloxyphenyl)-4-phenylbutadiene (206755-80-8) → 2-[2-(4-phenylbutyl)phenoxymethyl]oxirane (167145-62-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / H₂ / 5percent Pd/C / ethanol / 5 h / 60 °C

2: 100 percent / t-BuOK / N,N-dimethyl-acetamide / 0.33 h

With potassium tert-butylate; hydrogen; palladium on activated charcoal; In ethanol; N,N-dimethyl acetamide;

DOI:10.1248/cpb.46.639

upstream raw materials:

3-phenyl-propionaldehyde

Downstream raw materials:

2-(4-phenylbutyl)phenol

2-[2-(4-phenylbutyl)phenoxymethyl]oxirane

1-t-Butoxycarbonyl-2-{2-[2-(4-phenylbutyl)-phenoxy]ethyl}piperidine

1-tert-butoxycarbonyl-3-[2-(4-phenylbutyl)phenoxymethyl]piperidine