4-Methoxyphenyl tetramethylphosphorodiamidate

Base Information

• Chemical Name: 4-Methoxyphenyl tetramethylphosphorodiamidate
• CAS No.: 56184-96-4
• Molecular Formula: C₁₁H₁₉N₂O₃P
• Molecular Weight: 258.257
• Mol file: 56184-96-4.mol

Synonyms:4-Methoxyphenyl tetramethylphosphorodiamidate

Chemical Property of 4-Methoxyphenyl tetramethylphosphorodiamidate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-Methoxyphenyl tetramethylphosphorodiamidate

There total 2 articles about 4-Methoxyphenyl tetramethylphosphorodiamidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N,N,N',N'-Tetramethylphosphorodiamidic chloride (1605-65-8) + 4-methoxy-phenol (150-76-5) → 4-Methoxyphenyl tetramethylphosphorodiamidate (56184-96-4)

Guidance literature:

With sodium hydride; 1.) THF, 30 min, room temperature, 2.) THF, 12 h, room temperature;

DOI:10.1248/cpb.38.2637

Reference yield:

N,N,N,N,N,N-hexamethylphosphoric triamide (680-31-9) + 4-methoxy-phenol (150-76-5) → 4-Methoxyphenyl tetramethylphosphorodiamidate (56184-96-4)

Guidance literature:

at 229 - 230 ℃;

Reference yield: 91.0%

4-Methoxyphenyl tetramethylphosphorodiamidate (56184-96-4) + methyl iodide (74-88-4) → C12H21N2O3P (127136-76-9)

Guidance literature:

With sec.-butyllithium; 1.) cyclohexane, THF, -105 deg C, 1 h, 2.) cyclohexane, THF, -105 deg C, 1 h;

DOI:10.1248/cpb.38.2637

upstream raw materials:

N,N,N',N'-Tetramethylphosphorodiamidic chloride

4-methoxy-phenol

N,N,N,N,N,N-hexamethylphosphoric triamide

Downstream raw materials:

C₂₄H₂₉N₂O₄P

C₁₁H₁₉N₂O₃P

C₁₉H₂₇N₂O₅P

2-Methoxymethoxy-5-methoxytoluene