(2R,3S)-3-Azido-2-benzyloxy-3-phenyl-thiopropionic acid S-tert-butyl ester

Base Information

Chemical Name:(2R,3S)-3-Azido-2-benzyloxy-3-phenyl-thiopropionic acid S-tert-butyl ester
CAS No.:145041-34-5
Molecular Formula:C₂₀H₂₃N₃O₂S
Molecular Weight:369.488
Hs Code.:

Synonyms:(2R,3S)-3-Azido-2-benzyloxy-3-phenyl-thiopropionic acid S-tert-butyl ester

Suppliers and Price of (2R,3S)-3-Azido-2-benzyloxy-3-phenyl-thiopropionic acid S-tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3S)-3-Azido-2-benzyloxy-3-phenyl-thiopropionic acid S-tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3S)-3-Azido-2-benzyloxy-3-phenyl-thiopropionic acid S-tert-butyl ester

There total 3 articles about (2R,3S)-3-Azido-2-benzyloxy-3-phenyl-thiopropionic acid S-tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 145041-33-4
S-tert-butyl (2R,3R)-2-benzyloxy-3-hydroxy-3-phenylpropanethioate

: 145041-34-5
(2R,3S)-3-Azido-2-benzyloxy-3-phenyl-thiopropionic acid S-tert-butyl ester

Guidance literature:: With hydrogen azide; triphenylphosphine; diethylazodicarboxylate; In benzene; for 1h; Ambient temperature;
DOI:10.1016/S0040-4020(01)81916-5

Reference yield:

: 133756-18-0
S-tert-butyl 2-(benzyloxy)ethanethioate

: 145041-34-5
(2R,3S)-3-Azido-2-benzyloxy-3-phenyl-thiopropionic acid S-tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

2: triphenyphosphine, hydrazoic acid, diethyl azodicarboxylate / benzene / 1 h / Ambient temperature

With hydrogen azide; triphenylphosphine; diethylazodicarboxylate; In benzene;
DOI:10.1016/S0040-4020(01)81916-5

Reference yield:

: C₁₂H₁₆O₂S

: 145041-34-5
(2R,3S)-3-Azido-2-benzyloxy-3-phenyl-thiopropionic acid S-tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) TiCl₄, Et₃N, 2.) TBAF, HF / 1.) CH₂Cl₂, -78 deg C, 2.) CH₃CN, -78 to 0 deg C

2: HN₃, PPh₃, DEAD / benzene; tetrahydrofuran / Ambient temperature

With tris-(2-chloro-ethyl)-amine; hydrogen fluoride; tetrabutyl ammonium fluoride; titanium tetrachloride; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; benzene;
DOI:10.1016/S0957-4166(00)86030-9