Technology Process of C20H34O3Si
There total 6 articles about C20H34O3Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at 20 ℃;
for 0.75h;
DOI:10.1021/ol202515x
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C
1.2: 0 - 20 °C
2.1: diisobutylaluminium hydride / dichloromethane / 1 h / -78 °C
3.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.75 h / 20 °C
With
dmap; sodium hydride; diisobutylaluminium hydride; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; dichloromethane; mineral oil;
1.2: Wittig-Horner olefination;
DOI:10.1021/ol202515x
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: camphor-10-sulfonic acid / dichloromethane / 19 h / 20 °C
2.1: diisobutylaluminium hydride / dichloromethane / 1.5 h / -78 °C
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 - -45 °C
3.2: -45 - 20 °C
4.1: sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C
4.2: 0 - 20 °C
5.1: diisobutylaluminium hydride / dichloromethane / 1 h / -78 °C
6.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.75 h / 20 °C
With
dmap; oxalyl dichloride; camphor-10-sulfonic acid; sodium hydride; diisobutylaluminium hydride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; dichloromethane; mineral oil;
3.1: Swern oxidation / 3.2: Swern oxidation / 4.2: Wittig-Horner olefination;
DOI:10.1021/ol202515x
