(R)-2-tert-butoxycarbonylamino-4-(4-heptyloxy-phenyl)-2-methyl-butyric acid

Base Information

• Chemical Name: (R)-2-tert-butoxycarbonylamino-4-(4-heptyloxy-phenyl)-2-methyl-butyric acid
• CAS No.: 863991-38-2
• Molecular Formula: C₂₃H₃₇NO₅
• Molecular Weight: 407.55
• Mol file: 863991-38-2.mol

Synonyms:(R)-2-tert-butoxycarbonylamino-4-(4-heptyloxy-phenyl)-2-methyl-butyric acid

Chemical Property of (R)-2-tert-butoxycarbonylamino-4-(4-heptyloxy-phenyl)-2-methyl-butyric acid

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of (R)-2-tert-butoxycarbonylamino-4-(4-heptyloxy-phenyl)-2-methyl-butyric acid

There total 1 articles about (R)-2-tert-butoxycarbonylamino-4-(4-heptyloxy-phenyl)-2-methyl-butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

[(R)-1-formyl-3-(4-heptyloxy-phenyl)-1-methyl-propyl]-carbamic acid tert-butyl ester (863991-39-3) → (R)-2-tert-butoxycarbonylamino-4-(4-heptyloxy-phenyl)-2-methyl-butyric acid (863991-38-2)

Guidance literature:

With sodium chlorite; potassium dihydrogenphosphate; 2,3-Dimethyl-2-butene; In tert-butyl alcohol; at 20 ℃;

DOI:10.1016/j.bmcl.2010.01.118

Reference yield: 50.0%

(R)-2-tert-butoxycarbonylamino-4-(4-heptyloxy-phenyl)-2-methyl-butyric acid (863991-38-2) → (R)-2-amino-4-(4-heptyloxy-phenyl)-2-methyl-butanoic acid

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃;

DOI:10.1016/j.bmcl.2010.01.118

upstream raw materials:

[(R)-1-formyl-3-(4-heptyloxy-phenyl)-1-methyl-propyl]-carbamic acid tert-butyl ester