Technology Process of 1-(3,4-Diacetoxyphenyl)-7--8-oxa-3,4,6-triazaspiro<4.4>nona-3,6-dien-9-one
There total 5 articles about 1-(3,4-Diacetoxyphenyl)-7--8-oxa-3,4,6-triazaspiro<4.4>nona-3,6-dien-9-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
In
diethyl ether; dichloromethane;
for 24h;
Ambient temperature;
DOI:10.1021/jo00172a061
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1) N-methylmorpholine, isobutyl chloroformate, 2) NaOH / 1) THF, 0 degC, 25 min, 2) H2O, 0 degC, 30 min
2: Ac2O/NaOAc / 48 h / Ambient temperature
3: CF3COOH / CH2Cl2 / Ambient temperature
4: 81.1 percent / CH2Cl2; diethyl ether / 24 h / Ambient temperature
With
4-methyl-morpholine; sodium hydroxide; sodium acetate; acetic anhydride; trifluoroacetic acid; isobutyl chloroformate;
In
diethyl ether; dichloromethane;
DOI:10.1021/jo00172a061
- Guidance literature:
-
Multi-step reaction with 3 steps
1: Ac2O/NaOAc / 48 h / Ambient temperature
2: CF3COOH / CH2Cl2 / Ambient temperature
3: 81.1 percent / CH2Cl2; diethyl ether / 24 h / Ambient temperature
With
sodium acetate; acetic anhydride; trifluoroacetic acid;
In
diethyl ether; dichloromethane;
DOI:10.1021/jo00172a061
