TERT-BUTYL HYDROGEN PHTHALATE

Base Information

• Chemical Name: TERT-BUTYL HYDROGEN PHTHALATE
• CAS No.: 33693-84-4
• Molecular Formula: C12H14 O4
• Molecular Weight: 222.241
• Hs Code.: 2918990090
• Mol file: 33693-84-4.mol

Synonyms:1,2-Benzenedicarboxylicacid, mono(1,1-dimethylethyl) ester (9CI); Phthalic acid, mono-tert-butyl ester(8CI); Phthalic acid, tert-butyl ester (6CI,7CI); Mono-tert-butyl phthalate

Chemical Property of TERT-BUTYL HYDROGEN PHTHALATE

Chemical Property:

• Vapor Pressure: 1.72E-05mmHg at 25°C
• Melting Point: 79-80°C
• Boiling Point: 349.8°Cat760mmHg
• Flash Point: 131.8°C
• PSA: 63.60000
• Density: 1.173g/cm³
• LogP: 2.34010
• Water Solubility.: Insoluble in water.

Purity/Quality:

99% ^*data from raw suppliers

2-(tert-Butoxycarbonyl)benzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.
• Hazard Codes: R36/37/38:Irritating to eyes, respiratory system and skin.
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: It finds its application in the resolution and reactions of tertiary alcohols : 2-phenylbutan-2-ol and 3-methylhexan-3-ol.

Technology Process of TERT-BUTYL HYDROGEN PHTHALATE

There total 5 articles about TERT-BUTYL HYDROGEN PHTHALATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

Phthalic acid 1-tert-butyl ester 2-prop-2-ynyl ester (182342-95-6) → phthalic acid mono-tert-butyl ester (33693-84-4)

Guidance literature:

With benzyltriethylammonium tetrathiomolybdate; In acetonitrile; at 25 ℃; for 48h;

DOI:10.1039/cc9960001957

Reference yield: 80.0%

tert.-butylhydroperoxide (75-91-2) + benzocyclobutene-1,2-dione (6383-11-5) → phthalic acid mono-tert-butyl ester (33693-84-4)

Guidance literature:

In benzene; at 50 ℃; for 1h;

Reference yield:

phthalic anhydride (85-44-9) + tert-butyl alcohol (75-65-0) → phthalic acid mono-tert-butyl ester (33693-84-4)

Guidance literature:

With triethylamine;

upstream raw materials:

phthalic anhydride

tert-butyl alcohol

tert.-butylhydroperoxide

benzocyclobutene-1,2-dione

Downstream raw materials:

N-(1-cyclohexyl-5-ethyl-hexahydro-2,4,6-trioxo-5-pyrimidinyl)phthalamic acid tert-butyl ester

benzoic acid tert-butyl ester

1-(3,4-Diacetoxyphenyl)-7--8-oxa-3,4,6-triazaspiro<4.4>nona-3,6-dien-9-one

2--4-<1-(3,4-diacetoxyphenyl)ethylidene>-5-oxazolone

Refernces

• 1、 Ilankumaran, Palanichamy,Manoj,Chandrasekaran, Srinivasan. "Prop-2-ynyl as a protective group for carboxylic acids: A mild method for the highly selective deprotection of prop-2-ynyl esters using tetrathiomolybdate". . p. 1957 - 1958. Retrieved 2007/10/03.