O-(p-Toluenesulfonyl)-3-(4-Fluorophenoxy)propanol

Base Information

Chemical Name:O-(p-Toluenesulfonyl)-3-(4-Fluorophenoxy)propanol
CAS No.:223136-61-6
Molecular Formula:C₁₆H₁₇FO₄S
Molecular Weight:324.373
Hs Code.:
DSSTox Substance ID:DTXSID001176775

Synonyms:O-(p-Toluenesulfonyl)-3-(4-Fluorophenoxy)propanol;SCHEMBL7428076;LKZHUQWQCURSMV-UHFFFAOYSA-N;DTXSID001176775;223136-61-6;1-Propanol, 3-(4-fluorophenoxy)-, 1-(4-methylbenzenesulfonate)

Suppliers and Price of O-(p-Toluenesulfonyl)-3-(4-Fluorophenoxy)propanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of O-(p-Toluenesulfonyl)-3-(4-Fluorophenoxy)propanol

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:324.08315835
Heavy Atom Count:22
Complexity:404

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OCCCOC2=CC=C(C=C2)F

Technology Process of O-(p-Toluenesulfonyl)-3-(4-Fluorophenoxy)propanol

There total 2 articles about O-(p-Toluenesulfonyl)-3-(4-Fluorophenoxy)propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 104413-57-2
3-(4-fluorophenoxy)-1-propanol

: 98-59-9
p-toluenesulfonyl chloride

: 223136-61-6
O-(p-toluenesulfonyl)-3-(4-fluorophenoxy)propanol

Guidance literature:: In pyridine; (2S)-N-methyl-1-phenylpropan-2-amine hydrate;

Reference yield:

: 1579-78-8
3-(4-fluoro-phenoxy)propionic acid

: 223136-61-6
O-(p-toluenesulfonyl)-3-(4-fluorophenoxy)propanol

Guidance literature:: Multi-step reaction with 2 steps

1: borane / tetrahydrofuran; water

2: pyridine; (2S)-N-methyl-1-phenylpropan-2-amine hydrate

With borane; In tetrahydrofuran; pyridine; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; water;