3-(4-Fluorophenoxy)propionic acid

Base Information

Chemical Name:3-(4-Fluorophenoxy)propionic acid
CAS No.:1579-78-8
Molecular Formula:C9H9 F O3
Molecular Weight:184.167
Hs Code.:2918990090
European Community (EC) Number:216-424-6
UNII:5CS9VV5G5Y
DSSTox Substance ID:DTXSID90166326
Nikkaji Number:J120.456D
Wikidata:Q72475629
Mol file:1579-78-8.mol

Synonyms:3-(4-Fluorophenoxy)propionic acid;1579-78-8;3-(4-fluorophenoxy)propanoic acid;C9H9FO3;3-(4'-Fluorophenoxy)propionic acid;EINECS 216-424-6;MFCD00052838;Maybridge1_007558;3-(4-Fluorophenoxy)-propionic acid;3-(4-Fluoro-Phenoxy)-Propionic Acid;Propanoic acid, 3-(4-fluorophenoxy)-;5CS9VV5G5Y;SCHEMBL652824;HMS562P12;DTXSID90166326;3-(p-Fluorophenoxy)propionic acid;beta-(p-fluorophenoxy)propionic acid;AKOS000132460;3-[(4-fluorophenyl)oxy]propanoic acid;PS-6597;3-(4-FLUOROPHENOXY)PROPIONICACID;3-(4-Fluorophenoxy)propionic acid, 98%;AC-14117;CS-0204663;FT-0613664;EN300-31971;A809889;W-107999;Z240085178

Suppliers and Price of 3-(4-Fluorophenoxy)propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
3-(4-Fluorophenoxy)propionic acid 97%
1 g
$ 16.00

Sigma-Aldrich
3-(4-Fluorophenoxy)propionic acid 98%
25g
$ 138.00

Matrix Scientific
3-(4-Fluorophenoxy)propionic acid 97+%
5g
$ 46.00

Matrix Scientific
3-(4-Fluorophenoxy)propionic acid 97+%
1g
$ 16.00

Heterocyclics
3-(4-Fluorophenoxy)propanoicacid 97%
25g
$ 200.00

Heterocyclics
3-(4-Fluorophenoxy)propanoicacid 97%
100g
$ 550.00

Heterocyclics
3-(4-Fluorophenoxy)propanoicacid 97%
5g
$ 75.00

Crysdot
3-(4-Fluorophenoxy)propionic acid 97%
100g
$ 345.00

Atlantic Research Chemicals
3-(4-Fluorophenoxy)propanoicacid 95%
5gm:
$ 35.35

Apolloscientific
3-(4-Fluorophenoxy)propanoicacid 97%
1g
$ 15.00

Total 34 raw suppliers

Chemical Property of 3-(4-Fluorophenoxy)propionic acid

Chemical Property:

Melting Point:83-85 ºC
Boiling Point:287.7 °C at 760 mmHg
PKA:4.82±0.10(Predicted)
Flash Point:127.8 °C
PSA：46.53000
Density:1.267 g/cm³
LogP:1.67920
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:184.05357231
Heavy Atom Count:13
Complexity:164

Purity/Quality:

99%, ^*data from raw suppliers

3-(4-Fluorophenoxy)propionic acid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C,Xi
Statements: 36/37/38
Safety Statements: 26-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=CC=C1OCCC(=O)O)F
Uses 3-(4-Fluorophenoxy)propionic acid may be used as one of the reactants for the synthesis of 2,3-dihydro-6-fluoro-4H-1-benzopyran-4-one.

Technology Process of 3-(4-Fluorophenoxy)propionic acid

There total 7 articles about 3-(4-Fluorophenoxy)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 85169-02-4
3-(4-fluoro-phenoxy)propionitrile

: 1579-78-8
3-(4-fluoro-phenoxy)propionic acid

Guidance literature:: With hydrogenchloride; In water; at 80 - 90 ℃;
DOI:10.1016/j.tetlet.2021.153372

Reference yield:

: 107-94-8
chloropropionic acid

: 371-41-5
4-Fluorophenol

: 1579-78-8
3-(4-fluoro-phenoxy)propionic acid

Guidance literature:: With sodium hydroxide;
DOI:10.1021/ja01510a021

Reference yield:

: 371-40-4
4-fluoroaniline

: 1579-78-8
3-(4-fluoro-phenoxy)propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid; sodium nitrite; phosphoric acid / Erhitzen des Reaktionsgemisches mit Kupfer(II)-sulfat und wss. Schwefelsaeure auf 140grad

2: aq. NaOH solution

With sodium hydroxide; phosphoric acid; sulfuric acid; sodium nitrite;
DOI:10.1021/ja01510a021