1-{4-[2-(diphenylphosphanyl)naphthalen-1-yl]quinazolin-2-yl}cyclobutanecarbaldehyde

Base Information

Chemical Name:1-{4-[2-(diphenylphosphanyl)naphthalen-1-yl]quinazolin-2-yl}cyclobutanecarbaldehyde
CAS No.:1095559-89-9
Molecular Formula:C₃₅H₂₇N₂OP
Molecular Weight:522.586
Hs Code.:

Synonyms:1-{4-[2-(diphenylphosphanyl)naphthalen-1-yl]quinazolin-2-yl}cyclobutanecarbaldehyde

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Chemical Property of 1-{4-[2-(diphenylphosphanyl)naphthalen-1-yl]quinazolin-2-yl}cyclobutanecarbaldehyde

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Technology Process of 1-{4-[2-(diphenylphosphanyl)naphthalen-1-yl]quinazolin-2-yl}cyclobutanecarbaldehyde

There total 1 articles about 1-{4-[2-(diphenylphosphanyl)naphthalen-1-yl]quinazolin-2-yl}cyclobutanecarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1098229-39-0,1095559-81-1,1098229-44-7
(+/-)-2-cyclobutyl-4-(2-diphenylphosphanylnaphthalen-1-yl)quinazoline

: 109-94-4
formic acid ethyl ester

: 1095559-89-9
1-{4-[2-(diphenylphosphanyl)naphthalen-1-yl]quinazolin-2-yl}cyclobutanecarbaldehyde

Guidance literature:: (+/-)-2-cyclobutyl-4-(2-diphenylphosphanylnaphthalen-1-yl)quinazoline; With n-butyllithium; potassium tert-butylate; diisopropylamine; In tetrahydrofuran; hexane; at -50 - -40 ℃; Inert atmosphere;

formic acid ethyl ester; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/ejoc.200800650