2'-hydroxymethyl-2-methylpapaverinium iodide

Base Information

• Chemical Name: 2'-hydroxymethyl-2-methylpapaverinium iodide
• CAS No.: 50450-16-3
• Molecular Formula: C₂₂H₂₆NO₅*I
• Molecular Weight: 511.357
• Mol file: 50450-16-3.mol

Synonyms:2'-hydroxymethyl-2-methylpapaverinium iodide

Chemical Property of 2'-hydroxymethyl-2-methylpapaverinium iodide

Chemical Property:

Purity/Quality:

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Technology Process of 2'-hydroxymethyl-2-methylpapaverinium iodide

There total 1 articles about 2'-hydroxymethyl-2-methylpapaverinium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2'-hydroxymethylpapaverine (18017-47-5) + methyl iodide (74-88-4) → 2'-hydroxymethyl-2-methylpapaverinium iodide (50450-16-3)

Guidance literature:

In acetonitrile; at 80 ℃; for 2h;

DOI:10.1135/cccc19800956

Reference yield: 55.0%

2'-hydroxymethyl-2-methylpapaverinium iodide (50450-16-3) → 6'-Hydroxymethyl-laudanosine (50461-20-6)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 4h; Heating;

DOI:10.1002/ardp.19883210104

Reference yield:

2'-hydroxymethyl-2-methylpapaverinium iodide (50450-16-3) → (+/-)-1,3-Dideutero-6'-hydroxymethyllaudanosine

Guidance literature:

With sodium borodeuteride; In ethanol; for 4h; Heating;

DOI:10.1002/ardp.19883210104

upstream raw materials:

2'-hydroxymethylpapaverine

methyl iodide

Downstream raw materials:

6'-Hydroxymethyl-laudanosine