ditetradecyl N-<4-<(6-bromohexyl)oxy>benzoyl>-L-glutamate

Base Information

• Chemical Name: ditetradecyl N-<4-<(6-bromohexyl)oxy>benzoyl>-L-glutamate
• CAS No.: 130860-39-8
• Molecular Formula: C₄₆H₈₀BrNO₆
• Molecular Weight: 823.048
• Mol file: 130860-39-8.mol

Synonyms:ditetradecyl N-<4-<(6-bromohexyl)oxy>benzoyl>-L-glutamate

Chemical Property of ditetradecyl N-<4-<(6-bromohexyl)oxy>benzoyl>-L-glutamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ditetradecyl N-<4-<(6-bromohexyl)oxy>benzoyl>-L-glutamate

There total 4 articles about ditetradecyl N-<4-<(6-bromohexyl)oxy>benzoyl>-L-glutamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-<(6-bromohexyl)oxy>benzoic acid (98033-73-9) + bis(tetradecyl) L-glutamate hydrochloride (125401-72-1) → ditetradecyl N-<4-<(6-bromohexyl)oxy>benzoyl>-L-glutamate (130860-39-8)

Guidance literature:

With diethyl cyanophosphonate; triethylamine; In tetrahydrofuran; for 24h; Ambient temperature;

DOI:10.1021/ja00002a034

Reference yield:

Ethyl 4-hydroxybenzoate (120-47-8) → ditetradecyl N-<4-<(6-bromohexyl)oxy>benzoyl>-L-glutamate (130860-39-8)

Guidance literature:

Multi-step reaction with 3 steps

1: KOH / ethanol / 7 h / Heating

2: 30percent aq. hydrobromic acid / acetic acid; ethanol / 7 h / Heating

3: 86 percent / triethylamine, diethyl phosphocyanide / tetrahydrofuran / 24 h / Ambient temperature

With potassium hydroxide; diethyl cyanophosphonate; hydrogen bromide; triethylamine; In tetrahydrofuran; ethanol; acetic acid;

DOI:10.1021/ja00002a034

Reference yield:

1 ,6-dibromohexane (629-03-8) → ditetradecyl N-<4-<(6-bromohexyl)oxy>benzoyl>-L-glutamate (130860-39-8)

Guidance literature:

Multi-step reaction with 3 steps

1: KOH / ethanol / 7 h / Heating

2: 30percent aq. hydrobromic acid / acetic acid; ethanol / 7 h / Heating

3: 86 percent / triethylamine, diethyl phosphocyanide / tetrahydrofuran / 24 h / Ambient temperature

With potassium hydroxide; diethyl cyanophosphonate; hydrogen bromide; triethylamine; In tetrahydrofuran; ethanol; acetic acid;

DOI:10.1021/ja00002a034

upstream raw materials:

4-<(6-bromohexyl)oxy>benzoic acid

bis(tetradecyl) L-glutamate hydrochloride

Ethyl 4-hydroxybenzoate

1 ,6-dibromohexane

Downstream raw materials:

ditetradecyl N-<4-<<6-(trimethylammonio)hexyl>oxy>benzoyl>-L-glutamate bromide