dimethyl 5-(diethoxyphosphoryl)isophthalate

Base Information

• Chemical Name: dimethyl 5-(diethoxyphosphoryl)isophthalate
• CAS No.: 210969-59-8
• Molecular Formula: C₁₄H₁₉O₇P
• Molecular Weight: 330.274
• Mol file: 210969-59-8.mol

Synonyms:dimethyl 5-(diethoxyphosphoryl)isophthalate

Chemical Property of dimethyl 5-(diethoxyphosphoryl)isophthalate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of dimethyl 5-(diethoxyphosphoryl)isophthalate

There total 9 articles about dimethyl 5-(diethoxyphosphoryl)isophthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

Diethyl phosphate (598-02-7) + dimethyl 5-bromoisophthalate (51760-21-5) → dimethyl 5-(diethoxyphosphoryl)isophthalate (210969-59-8)

Guidance literature:

With palladium diacetate; triethylamine; triphenylphosphine; In toluene; at 90 ℃; for 20h; Inert atmosphere;

DOI:10.1039/b917987a

Reference yield: 42.0%

5-iodo-isophthalic acid dimethyl ester (51839-15-7) + phosphonic acid diethyl ester (762-04-9) → dimethyl 5-(diethoxyphosphoryl)isophthalate (210969-59-8)

Guidance literature:

With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 90 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ja500356z

Reference yield:

5-iodo-isophthalic acid dimethyl ester (51839-15-7) + triethyl phosphite (122-52-1) → dimethyl 5-(diethoxyphosphoryl)isophthalate (210969-59-8)

Guidance literature:

With nickel dibromide; at 160 - 175 ℃; for 14h;

upstream raw materials:

Diethyl phosphate

dimethyl 5-bromoisophthalate

5-iodoisophthalic acid dichloride

5-iodo-isophthalic acid dimethyl ester

Downstream raw materials:

di-n-butyl 3,5-dimethoxycarbonylphenylphosphonate

dimethyl 5-(diisopropyloxyphosphoryl)isophthalate

Refernces

• 1、 -. "Phosphonic chloride monomer, nanofiltration composite membrane and preparation method of nanofiltration composite membrane". Paragraph 0077; 0078. . Retrieved 2017/10/07.
• 2、 Bazaga-García, Montse,Colodrero, Rosario M. P.,Papadaki, Maria,Garczarek, Piotr,Zoń, Jerzy,Olivera-Pastor, Pascual,Losilla, Enrique R.,León-Reina, Laura,Aranda, Miguel A. G.,Choquesillo-Lazarte, Duane,Demadis, Konstantinos D.,Cabeza, Aurelio. "Guest molecule-responsive functional calcium phosphonate frameworks for tuned proton conductivity". . p. 5731 - 5739. Retrieved 2014/05/06.