51760-21-5

Usage

Uses

Used in Pharmaceutical Industry:
DIMETHYL 5-BROMOISOPHTHALATE is used as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its chemical properties make it a valuable component in the development of pharmaceutical products, contributing to the effectiveness and safety of these medications.

InChI:InChI=1/C10H9BrO4/c1-14-9(12)6-3-7(10(13)15-2)5-8(11)4-6/h3-5H,1-2H3

Upstream product

• 67-56-1 methanol 
• 23351-91-9 5-bromoisophthalic acid 
• 1459-93-4 dimethyl Isophthalate 
• 74-88-4 methyl iodide 
• 121-91-5 isophthalic acid 
• 57863-69-1 5-bromobenzene-1,3-dicarboxylic acid chloride 
• 51839-15-7 5-iodo-isophthalic acid dimethyl ester 
• 99-27-4 dimethyl 5-aminoisophthalate 

Downstream Products

• 21991-00-4 1,3-dimethyl 5-phenylbenzene-1,3-dicarboxylate 
• 217655-36-2 dimethyl 5-(2-phenyl-1-ethynyl)isophthalate 
• 444992-78-3 methyl 3-acetyl-5-bromobenzoate 
• 953080-00-7 1-bromo-3,5-bis(1-hydroxy-1-methylethyl)benzene 
• 23351-91-9 5-bromoisophthalic acid 
• 307353-32-8 3-bromo-5-hydroxymethylbenzoic acid methyl ester 
• 51760-22-6 5-bromo-1,3-dihydroxymethylbenzene 
• 848499-85-4 dimethyl 5-(4-tert-butoxycarbonylaminopiperidin-1-yl)isophthalate 
• 1067652-07-6 dimethyl 5-(pyridin-3-yl)isophthalate 
• 1221400-20-9 5-(2-oxo-oxazolidin-3-yl)-isophthalic acid dimethyl ester 
• 1221400-16-3 5-(5-methyl-1,1-dioxo-1λ6-[1,2,5]thiadiazolidin-2-yl)-isophthalic acid dimethyl ester 
• 1221509-70-1 C₁₄H₁₄O₆ 
• 1421351-58-7 C₃₄H₂₆O₄ 
• 1421351-60-1 C₄₆H₄₂O₄ 

Relevant academic research and scientific papers

Novel microporous metal-organic framework exhibiting high acetylene and methane storage capacities

A new organic hexacarboxylic acid, 5,5′,5″-(9H-carbazole-3,6,9-triyl)triisophthalic acid (H6CTIA), was developed to construct its first microporous metal-organic framework (MOF), Cu6(CTIA)2 (ZJU-70). With open metal sites and suitable pore sizes, this MOF exhibits high acetylene and methane storage capacities at room temperature.

COMPOSITIONS AND METHODS FOR SELECTIVE SEPARATION OF HYDROCARBON ISOMERS

The present invention relates to novel metal-organic frameworks (MOFs) comprising tetratopic linkers with small pore apertures. The present invention further relates to methods of utilizing the MOFs of the invention to separate hydrocarbons through adsorptive processes. The present invention further relates to the discovery that Ca(H2tcpb) metal-organic framework (MOF) is capable of separating hydrocarbon isomers from one another through absorptive processes. In one aspect, the invention provides a method of separating C5-C8 hydrocarbon isomers, such that straight chain, mono-branched, and/or multi-branched isomers are each separated from one another. In certain embodiments, this separation is achieved by taking advantage of the temperature dependent adsorptive properties of Ca(H2tcpb) MOF.

Preparation method of room-temperature phosphorescent benzoate compound

The invention relates to a room-temperature phosphorescent benzoate compound. The benzoate compound is prepared by an efficient one-step method, and the prepared benzoate compound has obvious phosphorescence at room temperature, thereby broadening the application range of the benzoate compound. The product can be widely applied to phosphorescent materials.

A novel methoxy-decorated metal-organic framework exhibiting high acetylene and carbon dioxide storage capacities

A methoxy-decorated novel metal-organic framework (MOF), Cu2(DTPD) (ZJU-12, H4DTPD = 5,5′-(2,6-dimethoxynaphthalene-1,5-diyl)diisophthalic acid) with optimized pore space and open metal sites, was solvothermally synthesized and structurally characterized. The activated ZJU-12a displays a moderately high BET (Brunauer-Emmett-Teller) surface area of 2316 m2 g?1. Due to the pore size of the crystal being consistent with the molecular size and kinetic diameters of C2H2 and CO2, ZJU-12a exhibits a high C2H2 storage capacity of 244 cm3 g?1 and CO2 capture capacity of 134 cm3 g?1 at room temperature.

A New Microporous Metal-Organic Framework for Highly Selective C2H2/CH4 and C2H2/CO2 Separation at Room Temperature

We have successfully designed and synthesized a new tetracarboxylic linker, which constructed its first three-dimensional microporous metal-organic framework (MOF), [Cu2(DDPD)(H2O)2]?Gx (ZJU-13, H4DDPD=5,5'-(2,6-dihydroxynaphthalene-1,5-diyl)diisophthalic acid, ZJU=Zhejiang University, G = guest molecules) via solvothermal reaction. Due to open Cu2+ sites and optimized pore size, the activated ZJU-13a displays high separation selectivity for C2H2/CH4 of 74 and C2H2/CO2 of 12.5 at low pressure by using Ideal Adsorbed Solution Theory (IAST) simulation at room temperature.

Preparation method of novel 5-[4-(1-carboxyl naphthyl)]-isophthalic acid

The invention discloses a preparation method of novel 5-[4-(1-carboxyl naphthyl)]-isophthalic acid. 4-naphthoic acid is subjected to a methyl esterification reaction to generate a compound A 4-bromo-naphthoic acid methyl ester; 5-amino-dimethyl isophthalate is subjected to a diazotization bromination reaction to generate a compound B 5-bromo-dimethyl isophthalate; under the nitrogen protection condition, 5-bromo-dimethyl isophthalate and bis(pinacolato)diboron are subjected to a Miyaura boric acid esterification reaction by adding a catalyst to generate a compound C 3,5-dimethoxycarbonyl phenylboronic acid pinacol ester; the compound A and the compound C are subjected to a nitrogen protection reaction under the action of a catalyst to generate a compound D 5-[4-(1-methoxycarbonyl naphthyl)]-dimethyl isophthalate; the target compound E 5-[4-(1-carboxyl naphthyl)]-isophthalic acid is generated through a hydrolysis reaction, wherein the target compound E is shown as the following formula (please see the formula in the description). The method has the advantages of being simple in synthesizing method, low in synthesizing cost, and high in yield and product purity.

Novel synthesis method for 5-[10-(9-carbosyl anthryl)]-isophthalic acid

The invention provides a novel synthesis method for 5-[10-(9-carbosyl anthryl)]-isophthalic acid. A diazotization bromination reaction is conducted on 5-amino-1,3-benzenedicarboxylic acid dimethyl ester to synthesize a compound A, namely, 5-bromine-1,3-benzenedicarboxylic acid dimethyl ester, and catalysts are added to 5-bromine-1,3-benzenedicarboxylic acid dimethyl ester under the condition of nitrogen protection to make 5-bromine-1,3-benzenedicarboxylic acid dimethyl ester react with bis(pinacolato)diboron so as to generate a compound B, namely, 3,5-bis(methoxycarbonylethyl)phenylboronic acid pinacol ester. In addition, anthracene-9-carboxylic acid is bromized to obtain a compound C, namely, 10-bromine-9-carboxylic acid, the compound C is subjected to methyl esterification to generate a compound D, namely, 10-bromine-9-anthracene methyl formate, and the compound D and the compound B are subjected to a nitrogen protection reaction under the effect of catalysts to generate a compound E, namely, 5-[10-(9-methoxycarbonyl group anthryl)]-benzenedicarboxylic acid dimethyl ester, and a target compound F, namely, 5-[10-(9-carboxyl anthryl)]-isophthalic acid through a hydrolysis reaction. The target compound F is shown in the figure.

ZINC COMPLEX

A zinc complex characterized in exhibiting an octahedral structure and being configured from repeating units represented by general formula (I): wherein L represents a linker region, and R1 represents a C1-4 alkyl group, which can have a halogen atom.

Zirconium(IV)-Benzene Phosphonate Coordination Polymers: Lanthanide and Actinide Extraction and Thermal Properties

Coordination polymers with different P/(Zr + P) molar ratios were prepared by combining aqueous solutions of Zr(IV) and benzenephosphonate derivatives. 1,3,5-Benzenetrisphosphonic acid (BTP) as well as phosphonocarboxylate derivatives in which carboxylate substitutes one or two of the phosphonate groups were chosen as the building blocks. The precipitates obtained on combining the two solutions were not X-ray amorphous but rather were indicative of poorly ordered materials. Hydrothermal treatment did not alter the structure of the materials produced but did result in improved crystalline order. The use of HF as a mineralizing agent during hydrothermal synthesis resulted in the crystallization of at least three relatively crystalline phases whose structure could not be determined owing to the complexity of the diffraction patterns. Gauging from the similarity of the diffraction patterns of all the phases, the poorly ordered precipitates and crystalline materials appeared to have similar underlying structures. The BTP-based zirconium phosphonates all showed a higher selectivity for lanthanides and thorium compared with cations such as Cs+, Sr2+, and Co2+. Substitution of phosphonate groups by carboxylate groups did little to alter the pattern of selectivity implying that selectivity in the system was entirely determined by the -POH group with little influence from the -COOH groups. Samples with the highest phosphorus content showed the highest extraction efficiencies for lanthanide elements, especially the heavy lanthanides such as Dy3+ and Ho3+ with separation factors of around four with respect to La3+. In highly acid solutions (4 M HNO3) there was a pronounced variation in extraction efficiency across the lanthanide series. In situ, nonambient diffraction was performed on ZrBTP-0.8 loaded with Th, Ce, and a complex mixture of lanthanides. In all cases the crystalline Zr2P2O7 pyrophosphate phase was formed at ～800 °C demonstrating the versatility of this structure.

A NbO-type metal-organic framework exhibiting high deliverable capacity for methane storage

A copper-based NbO-type metal-organic framework ZJNU-50 constructed from a tetracarboxylate incorporating phenylethyne as a spacer exhibited an exceptionally high methane working capacity of 184 cm3 (STP) cm-3 for methane storage. The value is among the highest reported for MOF materials. This journal is