Potassium selenocyanate

Base Information

• Chemical Name: Potassium selenocyanate
• CAS No.: 3425-46-5
• Molecular Formula: CKNSe
• Molecular Weight: 144.076
• Hs Code.: 28429090
• Mol file: 3425-46-5.mol

Synonyms:Selenocyanic acid, potassium salt;

Chemical Property of Potassium selenocyanate

Chemical Property:

• Appearance/Colour: white to light beige crystalline powder or needles
• Vapor Pressure: 8.18mmHg at 25°C
• Melting Point: 147 °C
• Boiling Point: 134.2oC at 760 mmHg
• Flash Point: 35oC
• PSA: 23.79000
• Density: 2.347 g/cm³

• LogP: -0.36402
• Storage Temp.: Poison room
• Sensitive.: Moisture Sensitive
• Water Solubility.: Soluble in water, ethanol, dimethyl formamide, hexamethylphosphoramide, acetonitrile and methanol. Slightly soluble in terahydro

Purity/Quality:

99% ^*data from raw suppliers

Potassium selenocyanate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,N
• Hazard Codes: T,N,T+
• Statements: 23/25-33-50/53-28-23
• Safety Statements: 20/21-28-45-60-61-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Potassium selenocyanate is used to prepare triphenylphosphine selenide by reacting with triphenylphosphine. It finds application in solid state NMR of heavy-metal nuclei which results in the preparation of several mercury thiocyanate and selenocyanate compounds. Increasing interest in solid state NMR of heavy-metal nuclei results in the preparation of several Hg-thiocyanate and selenocyanate compounds as potential models. Bowmaker, G.A. et al. Inorg. Chem. 1998, 37, 1734. Increasing interest in solid state NMR of heavy-metal nuclei results in the preparation of several Hg-thiocyanate and selenocyanate compounds as potential models.

Technology Process of Potassium selenocyanate

There total 12 articles about Potassium selenocyanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

potassium cyanide + selenium (7782-49-2) → potassium selenocyanate (3425-46-5)

Guidance literature:

In ethanol; for 4h; Inert atmosphere; Reflux;

DOI:10.1002/chem.202102058

Reference yield: 94.0%

potassium cyanide → potassium selenocyanate (3425-46-5)

Guidance literature:

With selenium; In methanol; at 20 ℃; for 1h;

DOI:10.1021/acs.oprd.9b00380

Reference yield: 67.0%

potassium cyanide + selenium → potassium selenocyanate (3425-46-5)

Guidance literature:

With acetone; In melt; mixt. of KCN and Se heated to melting, allowed to stand for 15 min at room temp., dry acetone added dropwise, refluxed for 2 h; allowed to stand for 2 h in dark, concd. in vac., filtered, washed with cold ether;

DOI:10.1002/zaac.200400438

upstream raw materials:

potassium cyanide

selenium

monoselenotetrathionate^(2-)

potassium cyanate

Downstream raw materials:

(1-Methoxy-2-selenocyanato-ethyl)-benzene

(1-Propoxy-2-selenocyanato-ethyl)-benzene

(1-Ethoxy-2-selenocyanato-ethyl)-benzene

(1-Chloro-2-selenocyanato-ethyl)-benzene

Refernces

Synthesis of unnatural selenocystines and β-aminodiselenides via regioselective ring-opening of sulfamidates using a sequential, one-pot, multistep strategy

10.1021/jo1001388

The research focuses on the development of a novel method for synthesizing a variety of N-alkyl-β-aminodiselenides and selenocystine derivatives using a sequential, one-pot, multistep strategy. The key chemicals involved in this research include sulfamidates, potassium selenocyanate (KSeCN), and benzyltriethylammonium tetrathiomolybdate ([BnNEt3]2MoS4). These reagents play crucial roles in the regioselective ring-opening of sulfamidates and subsequent reductive dimerization to yield the desired products. The methodology is notable for its mild reaction conditions, high yields, and the tolerance of various protecting groups, making it a versatile approach for the synthesis of these compounds. The study also extends this methodology to the direct incorporation of selenocystine derivatives into peptides, demonstrating its potential application in peptide chemistry.