6-dodecyloxynaphthalene-2-carboxylic acid 4-formyl-3-hydroxyphenyl ester

Base Information

• Chemical Name: 6-dodecyloxynaphthalene-2-carboxylic acid 4-formyl-3-hydroxyphenyl ester
• CAS No.: 1036016-31-5
• Molecular Formula: C₃₀H₃₆O₅
• Molecular Weight: 476.613
• Mol file: 1036016-31-5.mol

Synonyms:6-dodecyloxynaphthalene-2-carboxylic acid 4-formyl-3-hydroxyphenyl ester

Chemical Property of 6-dodecyloxynaphthalene-2-carboxylic acid 4-formyl-3-hydroxyphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-dodecyloxynaphthalene-2-carboxylic acid 4-formyl-3-hydroxyphenyl ester

There total 5 articles about 6-dodecyloxynaphthalene-2-carboxylic acid 4-formyl-3-hydroxyphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

6-(dodecyloxy)naphthalene-2-carboxylic acid (106359-66-4) + 2,4-Dihydroxybenzaldehyde (95-01-2) → 6-dodecyloxynaphthalene-2-carboxylic acid 4-formyl-3-hydroxyphenyl ester (1036016-31-5)

Guidance literature:

6-(dodecyloxy)naphthalene-2-carboxylic acid; 2,4-Dihydroxybenzaldehyde; With dmap; at 20 ℃; for 0.5h; Cooling with ice;

With dicyclohexyl-carbodiimide; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2013.03.087

Reference yield:

6-Hydroxy-2-naphthoic acid (16712-64-4) → 6-dodecyloxynaphthalene-2-carboxylic acid 4-formyl-3-hydroxyphenyl ester (1036016-31-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sulfuric acid / 24 h / Reflux

2.1: potassium carbonate; potassium iodide / 24 h / Reflux; Inert atmosphere

3.1: potassium hydroxide / ethanol; water / 24 h / Reflux

4.1: dmap / 0.5 h / 20 °C / Cooling with ice

4.2: 24 h / 20 °C

With dmap; sulfuric acid; potassium carbonate; potassium iodide; potassium hydroxide; In ethanol; water;

DOI:10.1016/j.tet.2013.03.087

Reference yield:

6-dodecyloxynaphthalene-2-carboxylic acid methyl ester (1393721-72-6) → 6-dodecyloxynaphthalene-2-carboxylic acid 4-formyl-3-hydroxyphenyl ester (1036016-31-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium hydroxide / ethanol; water / 24 h / Reflux

2.1: dmap / 0.5 h / 20 °C / Cooling with ice

2.2: 24 h / 20 °C

With dmap; potassium hydroxide; In ethanol; water;

DOI:10.1016/j.tet.2013.03.087

upstream raw materials:

6-(dodecyloxy)naphthalene-2-carboxylic acid

2,4-Dihydroxybenzaldehyde

6-dodecyloxynaphthalene-2-carboxylic acid methyl ester

methyl 6-hydroxynaphthalene-2-carboxylate

Downstream raw materials:

6-dodecyloxynaphthalene-2-carboxylic acid 4-[(4-dodecyloxy-2-hydroxyphenylimino)methyl]-3-hydroxyphenyl ester