Technology Process of (+/-)-N-<2,4,5-Trimethoxy-3-methyl-6-(3,4,5,6-tetrahydro-2H-pyran-2-yloxymethyl)phenyl>succinimid
There total 10 articles about (+/-)-N-<2,4,5-Trimethoxy-3-methyl-6-(3,4,5,6-tetrahydro-2H-pyran-2-yloxymethyl)phenyl>succinimid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
molecular sieve; triethylamine;
In
toluene;
Heating;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 91 percent / PPTS / CH2Cl2 / Ambient temperature
2: 89 percent / H2, 80-percent hydrazine hydrate / Raney-Ni / ethanol; H2O / 1.) 30-40 deg.C, 2.) 1 h, reflux
3: 71 percent / Et3N, moleculare sieve / toluene / Heating
With
molecular sieve; hydrogen; pyridinium p-toluenesulfonate; hydrazine hydrate; triethylamine;
nickel;
In
ethanol; dichloromethane; water; toluene;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 89 percent / 60 percent NaH / dimethylformamide; paraffin / 12 h / Ambient temperature
2: 87 percent / potassium tert-butylate / dimethylsulfoxide / 1 h / Ambient temperature
3: 1) O3 ; 2) Zn, 50 percent acetic acid / 1) MeOH, -78 deg C ; 2) MeOH, -30 deg C - room t., 1 h
4: 73 percent / HNO3 , SnCl4 / CH2Cl2 / 1 h
5: 93 percent / NaCNBH3 / tetrahydrofuran; H2O / 1 h / ph 3.5 (acetic acid:THF:HCl, 10:8:1, v/v/v)
6: 91 percent / PPTS / CH2Cl2 / Ambient temperature
7: 89 percent / H2, 80-percent hydrazine hydrate / Raney-Ni / ethanol; H2O / 1.) 30-40 deg.C, 2.) 1 h, reflux
8: 71 percent / Et3N, moleculare sieve / toluene / Heating
With
molecular sieve; potassium tert-butylate; hydrogen; nitric acid; pyridinium p-toluenesulfonate; tin(IV) chloride; sodium hydride; sodium cyanoborohydride; ozone; hydrazine hydrate; acetic acid; triethylamine; zinc;
nickel;
In
tetrahydrofuran; ethanol; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene; paraffin;
