Chemical Property of Sodium decanoate
Chemical Property:
- Appearance/Colour:White crystalline
- Vapor Pressure:0.00355mmHg at 25°C
- Melting Point:~240 °C (dec.)
- Boiling Point:269.6 °C at 760 mmHg
- Flash Point:121.8 °C
- PSA：40.13000
- LogP:1.87700
- Storage Temp.:2-8°C
- Solubility.:H2O: 0.1 g/mL, clear, colorless
- Water Solubility.:very faint turbidity
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:8
- Exact Mass:194.12827413
- Heavy Atom Count:13
- Complexity:116
- Purity/Quality:
-
99% *data from raw suppliers
Sodium Decanoate *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- Safety Statements:
22-24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CCCCCCCCCC(=O)[O-].[Na+]
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Description
Decanoic acid is a medium-chain saturated fatty acid. It is a non-competitive antagonist at AMPA receptors that selectively reduces glutamate-induced currents in Xenopus oocytes expressing GluA2 and GluA3 subunit-containing AMPA receptors (IC50 = 0.52 mM) over those expressing GluA1 (IC50 = 2.09 mM) or GluA1 and GluA2 subunits (IC50 = 1.16 mM). It inhibits epileptiform activity induced by pentylenetetrazole or low magnesium in rat hippocampal slices. Decanoic acid (1 mM) induces contractions in isolated guinea pig duodenum, an effect that can be blocked by the muscarinic acetylcholine receptor antagonist hyoscine, voltage-gated sodium channel inhibitor tetrodotoxin (Item Nos. 14964 | 14963), or M2 muscarinic acetylcholine receptor antagonist hexamethonium . It increases the escape threshold in an orofacial mechanical stimulation test in rats when administered at a topical dose of 30% in ointment form, indicating analgesic activity. This effect can be blocked by the muscarinic acetylcholine receptor antagonist methoctramine . Plasma levels of decanoic acid are increased in patients with colorectal cancer when compared to patients with breast cancer or ulcerative colitis or without cancer.
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Uses
Sodium Caprate is the sodium salt of capric acid. It functions as a binder, emulsifier, and anticaking agent.
