C₁₈H₁₇NO₈

Base Information

• Chemical Name: C₁₈H₁₇NO₈
• CAS No.: 1356844-85-3
• Molecular Formula: C₁₈H₁₇NO₈
• Molecular Weight: 375.335
• Mol file: 1356844-85-3.mol

Synonyms:C₁₈H₁₇NO₈

Chemical Property of C₁₈H₁₇NO₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₈H₁₇NO₈

There total 1 articles about C₁₈H₁₇NO₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

ethyl (3-hydroxy-4-methoxyphenyl)acetate + 2-fluoro-5-nitrobenzoic acid (7304-32-7) → C18H17NO8 (1356844-85-3)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; at 80 ℃; for 8h;

DOI:10.1016/j.bmcl.2011.10.123

Reference yield: 100.0%

C18H17NO8 (1356844-85-3) → C18H19NO6 (1356844-86-4)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2011.10.123

Reference yield:

C18H17NO8 (1356844-85-3) → C26H25ClN2O6 (1356844-75-1)

Guidance literature:

Multi-step reaction with 4 steps

1: palladium on activated charcoal; hydrogen / ethanol / 1 h / 20 °C

2: triethylamine / dichloromethane / 3 h / 20 °C

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane / 24 h / 20 °C

4: water; lithium hydroxide / tetrahydrofuran; methanol / 2 h / 23 °C

With palladium on activated charcoal; water; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; lithium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane;

DOI:10.1016/j.bmcl.2011.10.123

upstream raw materials:

2-fluoro-5-nitrobenzoic acid

Downstream raw materials:

C₂₆H₂₅ClN₂O₆

C₂₇H₂₇ClN₂O₆

C₂₇H₂₇ClN₂O₆

C₂₇H₂₈N₂O₆