2-Fluoro-5-nitrobenzoic acid

Base Information

Chemical Name:2-Fluoro-5-nitrobenzoic acid
CAS No.:7304-32-7
Molecular Formula:C7H4FNO4
Molecular Weight:185.111
Hs Code.:29163990
European Community (EC) Number:627-772-7
NSC Number:133450
DSSTox Substance ID:DTXSID90299880
Nikkaji Number:J1.129.995D,J374.724G
Wikidata:Q72475245
Mol file:7304-32-7.mol

Synonyms:NSC 133450;

Suppliers and Price of 2-Fluoro-5-nitrobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Fluoro-5-nitrobenzoic Acid
50g
$ 135.00

TRC
2-Fluoro-5-nitrobenzoic Acid
25g
$ 95.00

TCI Chemical
2-Fluoro-5-nitrobenzoic Acid >98.0%(GC)(T)
5g
$ 63.00

TCI Chemical
2-Fluoro-5-nitrobenzoic Acid >98.0%(GC)(T)
25g
$ 212.00

SynQuest Laboratories
2-Fluoro-5-nitrobenzoic acid 98%
100 g
$ 185.00

SynQuest Laboratories
2-Fluoro-5-nitrobenzoic acid 98%
25 g
$ 65.00

Sigma-Aldrich
2-Fluoro-5-nitrobenzoic acid 98%
5g
$ 30.00

Matrix Scientific
2-Fluoro-5-nitrobenzoic acid 97%
25g
$ 28.00

Matrix Scientific
2-Fluoro-5-nitrobenzoic acid 97%
5g
$ 10.00

Matrix Scientific
2-Fluoro-5-nitrobenzoic acid 97%
100g
$ 88.00

Total 92 raw suppliers

Chemical Property of 2-Fluoro-5-nitrobenzoic acid

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:4.03E-05mmHg at 25°C
Melting Point:142-144 °C(lit.)
Boiling Point:337.7 °C at 760 mmHg
PKA:2.54±0.10(Predicted)
Flash Point:158 °C
PSA：83.12000
Density:1.568 g/cm³
LogP:1.95530
Storage Temp.:Refrigerator
Solubility.:Soluble in chloroform, ethanol.
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:185.01243577
Heavy Atom Count:13
Complexity:227

Purity/Quality:

99% ^*data from raw suppliers

2-Fluoro-5-nitrobenzoic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1[N+](=O)[O-])C(=O)O)F
Uses 2-Fluoro-5-nitrobenzoic acid may be used in the synthesis of dibenz[b,f]oxazepin-11(10H)-ones, via the nucleophilic aromatic substitution (SNAr) of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH of various 2-aminophenols on solid support, synthesis of substituted dibenzazocines on solid support, via SNAr of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH function of the immobilized polysubstituted phenols, in the synthesis of oxazepines. 2-Fluoro-5-nitrobenzoic acid may be used in the synthesis of:dibenz[b,f]oxazepin-11(10H)-ones, via the nucleophilic aromatic substitution (SNAr) of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH of various 2-aminophenols on solid supportsynthesis of substituted dibenzazocines on solid support, via SNAr of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH function of the immobilized polysubstituted phenolsin the synthesis of oxazepines

Technology Process of 2-Fluoro-5-nitrobenzoic acid

There total 8 articles about 2-Fluoro-5-nitrobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%