(1S,2S,3R)-3-Azido-4-tert-butyldiphenylsilyloxy-2-hydroxy-1-(thiazol-2-yl)butanol

Base Information

Chemical Name:(1S,2S,3R)-3-Azido-4-tert-butyldiphenylsilyloxy-2-hydroxy-1-(thiazol-2-yl)butanol
CAS No.:308140-73-0
Molecular Formula:C₂₃H₂₈N₄O₃SSi
Molecular Weight:468.652
Hs Code.:

Synonyms:(1S,2S,3R)-3-Azido-4-tert-butyldiphenylsilyloxy-2-hydroxy-1-(thiazol-2-yl)butanol

Suppliers and Price of (1S,2S,3R)-3-Azido-4-tert-butyldiphenylsilyloxy-2-hydroxy-1-(thiazol-2-yl)butanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2S,3R)-3-Azido-4-tert-butyldiphenylsilyloxy-2-hydroxy-1-(thiazol-2-yl)butanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2S,3R)-3-Azido-4-tert-butyldiphenylsilyloxy-2-hydroxy-1-(thiazol-2-yl)butanol

There total 4 articles about (1S,2S,3R)-3-Azido-4-tert-butyldiphenylsilyloxy-2-hydroxy-1-(thiazol-2-yl)butanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 308140-87-6
(2S,3S)-4-tert-Butyldiphenylsilyloxy-2,3-epoxy-1-(thiazol-2-yl)butan-1-one

: 308140-73-0
(1S,2S,3R)-3-Azido-4-tert-butyldiphenylsilyloxy-2-hydroxy-1-(thiazol-2-yl)butanol

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / K-selectride / tetrahydrofuran / 1 h / -78 °C

2: 4.2 g / NaN₃; aq. NH₄Cl / methanol / 44 h / Heating

With sodium azide; potassium tri-sec-butyl-borohydride; ammonium chloride; In tetrahydrofuran; methanol; 1: Reduction / 2: Substitution;
DOI:10.1055/s-2000-7114

Reference yield:

: 131380-35-3
(2R,3R)-4-(tert-Butyldiphenylsilyloxy)-2,3-epoxybutan-1-al

: 308140-73-0
(1S,2S,3R)-3-Azido-4-tert-butyldiphenylsilyloxy-2-hydroxy-1-(thiazol-2-yl)butanol

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 12.33 h / -30 - 20 °C

2: Amberlite IR 120 / methanol / 6 h / 20 °C

3: 4.2 g / NaN₃; aq. NH₄Cl / methanol / 44 h / Heating

With sodium azide; Amberlite IR 120; ammonium chloride; In methanol; dichloromethane; 1: Addition / 2: Substitution / 3: Substitution;
DOI:10.1055/s-2000-7114

Reference yield:

: 1027573-79-0
2-{(S)-[(2S,3S)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-oxiranyl]-trimethylsilanyloxy-methyl}-thiazole

: 308140-73-0
(1S,2S,3R)-3-Azido-4-tert-butyldiphenylsilyloxy-2-hydroxy-1-(thiazol-2-yl)butanol

Guidance literature:: Multi-step reaction with 2 steps

1: Amberlite IR 120 / methanol / 6 h / 20 °C

2: 4.2 g / NaN₃; aq. NH₄Cl / methanol / 44 h / Heating

With sodium azide; Amberlite IR 120; ammonium chloride; In methanol; 1: Substitution / 2: Substitution;
DOI:10.1055/s-2000-7114