131380-35-3Relevant academic research and scientific papers
Stereocontrolled total synthesis of iminosugar 1,4-dideoxy-1,4-imino-D-iditol
Agostinelli, Sonia,De Angelis, Martina,Lucarini, Claudia,Primitivo, Ludovica,Ricelli, Alessandra,Righi, Giuliana,Sappino, Carla
, (2020/05/14)
The first stereocontrolled total synthesis of iminosugar 1,4-dideoxy-1,4-imino-D-iditol is described. The key step in our approach was the double diastereoselection in the asymmetric dihydroxylation (AD) of suitable optically active olefin, the chiral vin
Asymmetric routes toward polyhydroxylated pyrrolidines: Synthesis of 1,4-dideoxy-1,4-imino-D-galactitol and 1,4-dideoxy-1,4-imino-D-glucitol
Righi, Giuliana,Mandic', Emanuela,Sappino, Carla,Dema, Ergys,Bovicelli, Paolo
, p. 100 - 105 (2016/10/22)
Herein the total synthesis of the pyrrolidine alkaloids 1,4-dideoxy-1,4-imino-D-galactitol and its diastereoisomer 1,4-dideoxy-1,4-imino-D-glucitol is described, starting from a common optically active precursor. The key step in our approach was the doubl
Stereoselective total synthesis of multiplolide A and of a diastereoisomer
Reddy, Bandi Chennakesava,Bangade, Vikas Madhukar,Ramesh, Palakuri,Meshram, Harshadas Mitaram
, p. 266 - 274 (2013/03/28)
A stereoselective total synthesis of multiplolide A (1) and of its diastereoisomer 2 was described from easily accessible starting materials (Schemes 2-4). The synthetic strategy involves a Jacobsen resolution, Sharpless epoxidation, Swern oxidation, Yamaguchi reaction, and ring-closing metathesis (RCM). Copyright
Asymmetric syntheses of (-)-lentiginosine and an original pyrrolizidinic analogue thereof from a versatile epoxyamine intermediate
Ayad, Tahar,Genisson, Yves,Baltas, Michel
, p. 2626 - 2631 (2007/10/03)
Ready access to natural (-)-lentiginosine and its pyrrolizidinic analogue from a chiral vinylic epoxyamine in a straightforward five-step sequence is presented. Careful use of the RCM reaction on aminotriols 5 and 6 constitutes the key feature of the synt
A Stereochemically General Synthesis of 2-Deoxyhexoses via the Asymmetric Allylboration of 2,3-Epoxy Aldehydes
Roush, William R.,Straub, Julie A.,VanNieuwenhze, Michael S.
, p. 1636 - 1648 (2007/10/02)
A stereochemically general strategy for the synthesis of 2-deoxyhexoses is described.This new approach involves the asymmetric allylboration of epoxy aldehydes 12 and 13, prepared via the Sharpless asymmetric epoxidation reaction, as a means of establishi
