8-(2-(dimethyl(phenyl)silyl)ethyl)-3,4-dihydronaphthalen-1(2H)-one

Base Information

• Chemical Name: 8-(2-(dimethyl(phenyl)silyl)ethyl)-3,4-dihydronaphthalen-1(2H)-one
• CAS No.: 1323941-00-9
• Molecular Formula: C₂₀H₂₄OSi
• Molecular Weight: 308.495
• Mol file: 1323941-00-9.mol

Synonyms:8-(2-(dimethyl(phenyl)silyl)ethyl)-3,4-dihydronaphthalen-1(2H)-one

Chemical Property of 8-(2-(dimethyl(phenyl)silyl)ethyl)-3,4-dihydronaphthalen-1(2H)-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-(2-(dimethyl(phenyl)silyl)ethyl)-3,4-dihydronaphthalen-1(2H)-one

There total 3 articles about 8-(2-(dimethyl(phenyl)silyl)ethyl)-3,4-dihydronaphthalen-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,4-dihydronaphthalene-1(2H)-one (529-34-0) + dimethylphenylvinylsilane (1125-26-4) → 8-(2-(dimethyl(phenyl)silyl)ethyl)-3,4-dihydronaphthalen-1(2H)-one (1323941-00-9)

Guidance literature:

With (HCHO+4PPh₃)-Ru(II) supported on CeO₂; In toluene; at 140 ℃; for 3h; Inert atmosphere; Schlenk technique;

DOI:10.1246/bcsj.20180144

Reference yield:

C27H31NOSi → 8-(2-(dimethyl(phenyl)silyl)ethyl)-3,4-dihydronaphthalen-1(2H)-one (1323941-00-9)

Guidance literature:

With hydrogenchloride; water; In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/anie.201101823

Reference yield:

(E)-N-(3,4-dihydro-1(2H)-naphthalenylidene)-4-methoxybenzenamine (875296-48-3) + dimethylphenylvinylsilane (1125-26-4) → 8-(2-(dimethyl(phenyl)silyl)ethyl)-3,4-dihydronaphthalen-1(2H)-one (1323941-00-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 1,10-Phenanthroline; neopentylmagnesium bromide; cobalt(II) bromide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

1.2: 24 h / 20 °C / Inert atmosphere

2.1: hydrogenchloride; water / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

With hydrogenchloride; 1,10-Phenanthroline; water; neopentylmagnesium bromide; cobalt(II) bromide; In tetrahydrofuran;

DOI:10.1002/anie.201101823

upstream raw materials:

(E)-N-(3,4-dihydro-1(2H)-naphthalenylidene)-4-methoxybenzenamine

dimethylphenylvinylsilane

3,4-dihydronaphthalene-1(2H)-one