6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline

Base Information

Chemical Name:6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline
CAS No.:1032571-01-9
Molecular Formula:C₁₇H₂₆N₄O₃
Molecular Weight:334.418
Hs Code.:

Synonyms:6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline

Suppliers and Price of 6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline

Chemical Property:

Boiling Point:521.4±60.0 °C(Predicted)
Density:1.30±0.1 g/cm3(Predicted)

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline

There total 5 articles about 6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 4-{3-[4-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-nitrophenoxy]propyl}morpholine

: 1032571-01-9
6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline

Guidance literature:: With 5% Pd-1%Fe/C; hydrogen; potassium carbonate; at 40 ℃; for 24h; under 75007.5 Torr; Large scale;

Reference yield: 43.0%

: 1032570-98-1
2-amino-3-methoxy-4-(3-morpholin-4-ylpropoxy)benzonitrile

: 107-15-3,85404-18-8
ethylenediamine

: 1032571-01-9
6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline

Guidance literature:: With sulfur; at 100 ℃; for 3h;

Reference yield:

: 881-68-5
vanillin acetate

: 1032571-01-9
6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline

Guidance literature:: Multi-step reaction with 4 steps

1.1: nitric acid; sulfuric acid / dichloromethane; water / 12 h / 0 - 5 °C / Microwave irradiation; Large scale

1.2: 3 h / 30 °C / Large scale

1.3: 0.25 h / 30 °C / pH 0.5 - 1 / Large scale

2.1: acetonitrile / 0.83 h / 20 °C

2.2: 2 h / 20 °C

2.3: 3 h / Reflux

3.1: dichloromethane / 1.17 h / 20 °C / Large scale

3.2: 2.25 h / 0 - 25 °C / Large scale

4.1: 5% Pd-1%Fe/C; hydrogen; potassium carbonate / 24 h / 40 °C / 75007.5 Torr / Large scale

With sulfuric acid; 5% Pd-1%Fe/C; hydrogen; nitric acid; potassium carbonate; In dichloromethane; water; acetonitrile;