N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide

Base Information

Chemical Name:N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide
CAS No.:170985-85-0
Molecular Formula:C13H20N2O2
Molecular Weight:236.314
Hs Code.:
DSSTox Substance ID:DTXSID80436045
Nikkaji Number:J2.096.458H
Wikidata:Q72476700
Mol file:170985-85-0.mol

Synonyms:170985-85-0;2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde;N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide;N-[[(2S,3S)-2-phenylmethoxypentan-3-yl]amino]formamide;Hydrazinecarboxaldehyde, 2-[(1S,2S)-1-ethyl-2-(phenylmethoxy)propyl]-;2-((1s,2s)-1-ethyl-2-(phenylmethoxy)propyl)hydrazinecarboxaldehyde;N'-[(2S,3S)-2-(Benzyloxy)pentan-3-yl]formohydrazide;SCHEMBL12186606;DTXSID80436045;AMY14824;BCP08708;AKOS016002863;AC-8331;N'(2S,3S)-2-(Benzyloxy)pentan-3-yl] formohydrazide;2-[(1S,2S)-1-Ethyl-2-(benzyloxy)propyl]hydrazine-1-carbaldehyde;2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarbaldehyde

Suppliers and Price of N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde
500mg
$ 565.00

TRC
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde
1g
$ 1055.00

J&W Pharmlab
FormicacidN''-(2(S)-benzyloxy-1(S)-ethyl-propyl)-hydrazide 96%
1g
$ 980.00

J&W Pharmlab
FormicacidN''-(2(S)-benzyloxy-1(S)-ethyl-propyl)-hydrazide 96%
250mg
$ 350.00

Crysdot
N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide 95+%
1g
$ 332.00

American Custom Chemicals Corporation
2-[(1S,2S)-1-ETHYL-2-(PHENYLMETHOXY)PROPYL]HYDRAZINE CARBOXALDEHYDE 95.00%
1G
$ 735.00

Alichem
N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide
1g
$ 276.04

Total 64 raw suppliers

Chemical Property of N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide

Chemical Property:

Boiling Point:338.531 °C at 760 mmHg
PKA:13.30±0.23(Predicted)
Flash Point:158.538 °C
PSA：50.36000
Density:1.042 g/cm³
LogP:3.03860
Storage Temp.:2-8°C(protect from light)
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:236.152477885
Heavy Atom Count:17
Complexity:206

Purity/Quality:

99%, ^*data from raw suppliers

2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C(C)OCC1=CC=CC=C1)NNC=O
Isomeric SMILES:CC[C@@H]([C@H](C)OCC1=CC=CC=C1)NNC=O
Uses Posaconazole intermediate. Antifungal agent.

Technology Process of N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide

There total 18 articles about N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 74-96-4
ethyl bromide

: 170985-84-9
(S)-N'-(2-(benzyloxy)propylidene)formylhydrazide

: 170985-85-0
N’-[(1S,2S)-2-(benzyloxy)-1-ethylpropyl]formic hydrazide

Guidance literature:: ethyl bromide; With iodine; magnesium; In tert-butyl methyl ether; at 40 - 55 ℃; for 2h; Inert atmosphere;

(S)-N'-(2-(benzyloxy)propylidene)formylhydrazide; With N,O-bis-(trimethylsilyl)-acetamide; In tert-butyl methyl ether; at 5 - 30 ℃; for 9h; Temperature; Inert atmosphere;

Reference yield: 62.3%

: 925-90-6
ethylmagnesium bromide

: (S)-2-(Benzyloxy)-N-(Formylamino)-Propanimine

: 170985-85-0
N’-[(1S,2S)-2-(benzyloxy)-1-ethylpropyl]formic hydrazide

: N'-((2S,3R)-2-(benzyloxy)pent-3-yl)formylhydrazine

Guidance literature:: (S)-2-(Benzyloxy)-N-(Formylamino)-Propanimine; With N,N-bis(trimethylsilyl)acetamide; In diethyl ether; at 20 ℃; for 0.75h;

ethylmagnesium bromide; In diethyl ether; at 20 ℃;
DOI:10.1016/j.tetlet.2004.09.028