triisopropylsilyl-((N-tert-butoxycarbonyl)glycyl)-propargylamine

Base Information

• Chemical Name: triisopropylsilyl-((N-tert-butoxycarbonyl)glycyl)-propargylamine
• CAS No.: 1639198-69-8
• Molecular Formula: C₁₉H₃₆N₂O₃Si
• Molecular Weight: 368.592
• Mol file: 1639198-69-8.mol

Synonyms:triisopropylsilyl-((N-tert-butoxycarbonyl)glycyl)-propargylamine

Chemical Property of triisopropylsilyl-((N-tert-butoxycarbonyl)glycyl)-propargylamine

Chemical Property:

Purity/Quality:

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Technology Process of triisopropylsilyl-((N-tert-butoxycarbonyl)glycyl)-propargylamine

There total 1 articles about triisopropylsilyl-((N-tert-butoxycarbonyl)glycyl)-propargylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

BOC-glycine (4530-20-5) + 3-(triisopropylsilyl)prop-2-yn-1-amine (918871-51-9) → triisopropylsilyl-((N-tert-butoxycarbonyl)glycyl)-propargylamine (1639198-69-8)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 3h; Cooling with ice;

DOI:10.1039/c4md00013g

upstream raw materials:

BOC-glycine

3-(triisopropylsilyl)prop-2-yn-1-amine