4-<(allyloxy)methyl>-4-benzyl-10,19-diethyl-4,10,19-triaza-1,7,13,16-tetraoxycycloheneicosane

Base Information

• Chemical Name: 4-<(allyloxy)methyl>-4-benzyl-10,19-diethyl-4,10,19-triaza-1,7,13,16-tetraoxycycloheneicosane
• CAS No.: 118974-37-1
• Molecular Formula: C₂₉H₅₁N₃O₅
• Molecular Weight: 521.741
• Mol file: 118974-37-1.mol

Synonyms:4-<(allyloxy)methyl>-4-benzyl-10,19-diethyl-4,10,19-triaza-1,7,13,16-tetraoxycycloheneicosane

Chemical Property of 4-<(allyloxy)methyl>-4-benzyl-10,19-diethyl-4,10,19-triaza-1,7,13,16-tetraoxycycloheneicosane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-<(allyloxy)methyl>-4-benzyl-10,19-diethyl-4,10,19-triaza-1,7,13,16-tetraoxycycloheneicosane

There total 4 articles about 4-<(allyloxy)methyl>-4-benzyl-10,19-diethyl-4,10,19-triaza-1,7,13,16-tetraoxycycloheneicosane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

4-<(allyloxy)methyl>-1,8-diiodo-3,6-dioxaoctane (114719-16-3) + 9-benzyl-3,9,15-triaza-6,12-dioxaheptadecane (118974-42-8) → 4-<(allyloxy)methyl>-4-benzyl-10,19-diethyl-4,10,19-triaza-1,7,13,16-tetraoxycycloheneicosane (118974-37-1)

Guidance literature:

With sodium carbonate; potassium carbonate; sodium iodide; In acetonitrile; for 24h; Heating;

DOI:10.1021/jo00278a016

Reference yield:

N-[2-(2-hydroxyethoxy)ethyl]acetamide (118974-46-2) → 4-<(allyloxy)methyl>-4-benzyl-10,19-diethyl-4,10,19-triaza-1,7,13,16-tetraoxycycloheneicosane (118974-37-1)

Guidance literature:

Multi-step reaction with 4 steps

1: thionyl chloride

2: 71 percent / anhydrous Na₂CO₃ / toluene / 48 h / Heating

3: 73 percent / LiAlH₄ / tetrahydrofuran

With lithium aluminium tetrahydride; thionyl chloride; sodium carbonate; In tetrahydrofuran; toluene;

DOI:10.1016/0040-4039(88)85282-1

Reference yield:

N-[2-(2-chloroethoxy)ethyl]acetamide. N-[2-(2-hydroxyethoxy)ethyl]acetamide (118974-47-3) → 4-<(allyloxy)methyl>-4-benzyl-10,19-diethyl-4,10,19-triaza-1,7,13,16-tetraoxycycloheneicosane (118974-37-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 71 percent / anhydrous Na₂CO₃ / toluene / 48 h / Heating

2: 73 percent / LiAlH₄ / tetrahydrofuran

With lithium aluminium tetrahydride; sodium carbonate; In tetrahydrofuran; toluene;

DOI:10.1016/0040-4039(88)85282-1

upstream raw materials:

4-<(allyloxy)methyl>-1,8-diiodo-3,6-dioxaoctane

9-benzyl-3,9,15-triaza-6,12-dioxaheptadecane

N-[2-(2-hydroxyethoxy)ethyl]acetamide

N-[2-(2-chloroethoxy)ethyl]acetamide. N-[2-(2-hydroxyethoxy)ethyl]acetamide