(3R,4S)-1-Benzyl-3-hydroxy-4-(2-hydroxy-ethyl)-1-methyl-piperidinium; iodide

Base Information

Chemical Name:(3R,4S)-1-Benzyl-3-hydroxy-4-(2-hydroxy-ethyl)-1-methyl-piperidinium; iodide
CAS No.:124838-80-8
Molecular Formula:C₁₅H₂₄NO₂*I
Molecular Weight:377.266
Hs Code.:

Synonyms:(3R,4S)-1-Benzyl-3-hydroxy-4-(2-hydroxy-ethyl)-1-methyl-piperidinium; iodide

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Chemical Property of (3R,4S)-1-Benzyl-3-hydroxy-4-(2-hydroxy-ethyl)-1-methyl-piperidinium; iodide

Chemical Property:

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Technology Process of (3R,4S)-1-Benzyl-3-hydroxy-4-(2-hydroxy-ethyl)-1-methyl-piperidinium; iodide

There total 4 articles about (3R,4S)-1-Benzyl-3-hydroxy-4-(2-hydroxy-ethyl)-1-methyl-piperidinium; iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 98080-21-8,124838-77-3
3S,4RS-3-hydroxy-4-(2'-hydroxyethyl)-1-benzylpiperidine

: 74-88-4
methyl iodide

: 124838-80-8
(3R,4S)-1-Benzyl-3-hydroxy-4-(2-hydroxy-ethyl)-1-methyl-piperidinium; iodide

Guidance literature:: In acetone;

Reference yield:

: 3684-26-2,25333-42-0,34583-34-1,1619-34-7
(S)-quinuclidin-3-ol

: 124838-80-8
(3R,4S)-1-Benzyl-3-hydroxy-4-(2-hydroxy-ethyl)-1-methyl-piperidinium; iodide

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / CHCl₃ / 0.5 h / 25 °C

2: 17 percent / KOH / dimethylsulfoxide / 24 h / 60 °C

3: 100 percent / acetone

With potassium hydroxide; In chloroform; dimethyl sulfoxide; acetone;

Reference yield:

: 124838-72-8
(S)-N-benzyl-3-hydroxyquinuclidinium chloride

: 124838-80-8
(3R,4S)-1-Benzyl-3-hydroxy-4-(2-hydroxy-ethyl)-1-methyl-piperidinium; iodide

Guidance literature:: Multi-step reaction with 2 steps

1: 17 percent / KOH / dimethylsulfoxide / 24 h / 60 °C

2: 100 percent / acetone

With potassium hydroxide; In dimethyl sulfoxide; acetone;