4-(benzoyloxy)benzoyl cyanide

Base Information

• Chemical Name: 4-(benzoyloxy)benzoyl cyanide
• CAS No.: 100207-70-3
• Molecular Formula: C₁₅H₉NO₃
• Molecular Weight: 251.241
• Mol file: 100207-70-3.mol

Synonyms:4-(benzoyloxy)benzoyl cyanide

Chemical Property of 4-(benzoyloxy)benzoyl cyanide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(benzoyloxy)benzoyl cyanide

There total 2 articles about 4-(benzoyloxy)benzoyl cyanide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-(benzoyloxy)benzaldehyde cyanohydrin (100207-69-0) → 4-(benzoyloxy)benzoyl cyanide (100207-70-3)

Guidance literature:

With tert.-butylhydroperoxide; tris(triphenylphosphine)ruthenium(II) chloride; In benzene; for 5h; Ambient temperature;

DOI:10.1021/jo00356a029

Reference yield:

4-formylphenyl benzoate (5339-06-0) → 4-(benzoyloxy)benzoyl cyanide (100207-70-3)

Guidance literature:

Multi-step reaction with 2 steps

1: ZnI₂, HCl

2: 80 percent / t-BuOOH, RuCl₂(PPh₃)3 / 5 h

With hydrogenchloride; tert.-butylhydroperoxide; tris(triphenylphosphine)ruthenium(II) chloride; zinc(II) iodide;

Reference yield: 92.0%

4-(benzoyloxy)benzoyl cyanide (100207-70-3) → 4-cyanophenyl benzoate (16513-72-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 120 ℃; for 6h;

DOI:10.1021/jo00356a029

upstream raw materials:

4-(benzoyloxy)benzaldehyde cyanohydrin

4-formylphenyl benzoate

Downstream raw materials:

4-cyanophenyl benzoate